Methyl 6-chloro-4-hydroxypicolinate CAS 1256805-03-4
| CAS No. | 1256805-03-4 |
| Molecular Formula | C7H6ClNO3 |
| Molecular Weight | 187.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 6-chloro-4-hydroxypicolinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Methyl 6-chloro-4-hydroxypicolinate (CAS 1256805-03-4), molecular formula C7H6ClNO3 and molecular weight 187.58 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Methyl 6-chloro-4-hydroxypicolinate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 187.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H6ClNO3 |
| Molecular Weight | 187.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- Methyl 5-chloro-3-hydroxypicolinate (CAS 1256790-90-5)
- Methyl 2-Chloro-5-hydroxyisonicotinate (CAS 1256807-90-5)
- 5-Chloro-3-methoxypyridine-2-carboxylic acid (CAS 1256789-21-5)
- Methyl 6-chloro-5-hydroxypicolinate (CAS 1256808-87-3)
- 5-Amino-2-ethoxybenzoic acid hydrochloride (CAS 1269053-30-6)
- (1R,3R,4S)-2-[(tert-butoxy)carbonyl]-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid (CAS 134877-63-7)
- 1-Chloro-2-Buten-1-Ol-1-Acetate (CAS 85367-27-7)
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- 4-(4-Ethylphenyl)-2-hydrazinyl-6-(trifluoromethyl)pyrimidine (CAS 861439-49-8)
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- 6-Fluoro-5-nitroquinolin-2(1H)-one (CAS 1420794-56-4)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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