3-Amino-6-chloropyridin-2(1H)-one CAS 1256808-08-8
| CAS No. | 1256808-08-8 |
| Molecular Formula | C5H5ClN2O |
| Molecular Weight | 144.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 144.56 g/mol gives 3-Amino-6-chloropyridin-2(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Amino-6-chloropyridin-2(1H)-one (CAS 1256808-08-8), molecular formula C5H5ClN2O and molecular weight 144.56 g/mol, is a CATO reference standard with documented purity and traceability.
3-Amino-6-chloropyridin-2(1H)-one (C5H5ClN2O) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-6-chloropyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H5ClN2O |
| Molecular Weight | 144.56 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 2-Amino-4-chloro-3-hydroxypyridine (CAS 1003710-73-3)
- 2-amino-5-chloropyridin-4-ol (CAS 1121585-12-3)
- 3-Amino-4-chloropyridin-2(1H)-one (CAS 1198154-61-8)
- 5-Amino-6-chloropyridin-3-ol (CAS 1211537-54-0)
- 4-Amino-2-chloropyridin-3-ol (CAS 1227508-94-2)
- 5-Amino-6-chloropyridin-2-ol (CAS 1227581-42-1)
- 4-Amino-6-chloropyridin-2(1H)-one (CAS 1227600-15-8)
- 3-Amino-2-chloropyridin-4-ol (CAS 1242251-52-0)
Recommended Standards
- 5-Chloro-1-methyl-1H-imidazole-4-carbaldehyde (CAS 1256560-89-0)
- 2-Amino-3-chloropyridin-4-ol (CAS 1261269-43-5)
- 5-Chloro-3-cyclopropyl-1,2,4-oxadiazole (CAS 1247049-92-8)
- O-(3-Chloropyridin-2-yl)hydroxylamine (CAS 128080-08-0)
- 1-Allyl-3-(4,5-dihydronaphtho[1,2-d]thiazol-2-yl)urea (CAS 1206998-45-9)
- ZM 306416 Hydrochloride (CAS 196603-47-1)
- 2-Phenoxyethyl 7-(3,4-dimethoxyphenyl)-2-methyl-5-oxo-4-(thiophen-2-yl)-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 504432-11-5)
- (E)-(3-(4-chlorostyryl)-4-nitrophenyl)pentafluoro-lambda6-sulfane (CAS 1402089-66-0)
- Chlormethiazole hydrochloride, 98% (CAS 6001-74-7)
- tert-Butyl (1-bromoisoquinolin-3-yl)carbamate (CAS 890843-29-5)
- 6-Chloro-2-(trifluoromethyl)-1H-imidazo[4,5-c]pyridine (CAS 2384077-16-9)
- N-[2-(4-Ethylphenoxy)ethyl]-2-methoxyaniline (CAS 1040683-96-2)
- 2-((6,8-Dibromo-2-ethylquinazolin-4-yl)oxy)ethyl acetate (CAS 88624-87-7)
- Hexapeptide-10 (CAS 146439-94-3)
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