8-Bromo-1-(trifluoromethyl)isoquinoline CAS 1256808-82-8
| CAS No. | 1256808-82-8 |
| Molecular Formula | C10H5BrF3N |
| Molecular Weight | 276.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 8-Bromo-1-(trifluoromethyl)isoquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 8-Bromo-1-(trifluoromethyl)isoquinoline (CAS 1256808-82-8), a certified reference material (molecular formula C10H5BrF3N, MW 276.05 g/mol) for analytical method development and quality control.
The molecular framework of 8-Bromo-1-(trifluoromethyl)isoquinoline (C10H5BrF3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H5BrF3N |
| Molecular Weight | 276.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-Bromo-8-(trifluoromethyl)quinoline (CAS 1059064-11-7)
- 6-Bromo-8-(trifluoromethyl)quinoline (CAS 1065074-30-7)
- 4-Bromo-6-(trifluoromethyl)quinoline (CAS 1070879-32-1)
- 2-Bromo-6-(trifluoromethyl) quinoline (CAS 1101205-26-8)
- 1-Bromo-6-(trifluoromethyl)isoquinoline (CAS 1196152-93-8)
- 3-Bromo-7-(trifluoromethyl)quinoline (CAS 1215768-16-3)
- 5-Bromo-8-(trifluoromethyl)quinoline (CAS 1239460-75-3)
- 5-Bromo-3-(trifluoromethyl)quinoline (CAS 1239462-41-9)
Recommended Standards
- 7-Bromo-3-(trifluoromethyl)quinoline (CAS 1246549-93-8)
- 6-Bromo-1-(trifluoromethyl)isoquinoline (CAS 1256836-88-0)
- 5-Bromo-7-(trifluoromethyl)quinoline (CAS 1239462-77-1)
- 4-Fluoro-3-iodo-1-methyl-1H-indazole (CAS 1257535-07-1)
- Ethyl 2-fluoro-2-(thiophen-2-yl)acetate (CAS 94744-60-2)
- Boc-(s)-3-amino-3-(3-pyridyl)-propionic acid (CAS 297773-45-6)
- 5-(Bromomethyl)-2-methyloctane (CAS 1478668-09-5)
- Drotaverin Impurity 72 (CAS CATO-C4X-243572)
- 4-amino-1-methyl-2-oxo-1-azaspiro[4.5]dec-3-ene-3-carbonitrile (CAS 949873-93-2)
- 2-(4-Amino-2-chloro-5-methylphenyl)-2-(4-chlorophenyl)acetonitrile (CAS 61437-85-2)
- (4-(Methylthio)-2-(trifluoromethyl)phenyl)boronic acid (CAS 1072945-99-3)
- 6-(3-Fluorophenyl)imidazo[2,1-b]thiazol-5-amine (CAS 1432681-04-3)
- 1-(Tert-butyl) 4-ethyl 3-aminopiperidine-1,4-dicarboxylate (CAS 910332-54-6)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com