Methyl 3-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)phenyl)propanoate CAS 1256945-03-5
| CAS No. | 1256945-03-5 |
| Molecular Formula | C17H22BF3O4 |
| Molecular Weight | 358.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Methyl 3-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)phenyl)propanoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Methyl 3-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)phenyl)propanoate (CAS 1256945-03-5), a certified reference material (molecular formula C17H22BF3O4, MW 358.16 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 3-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(trifluoromethyl)phenyl)propanoate (C17H22BF3O4) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C17H22BF3O4 |
| Molecular Weight | 358.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Methyl Standards
- 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(thiophen-2-ylmethyl)urea (CAS 874301-80-1)
- 1,1,3,3-Tetramethyl-1,3-dioctyldisiloxane (CAS 18642-94-9)
- 1-Benzyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trimethylsilyl)-1H-1,2,3-triazole (CAS 1130489-19-8)
- 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrrole (CAS 1218790-43-2)
- 4,4,5,5-Tetramethyl-2-(4-((4-nitrophenyl)thio)phenyl)-1,3,2-dioxaborolane (CAS 2377606-31-8)
- 4,4,5,5-Tetramethyl-2-(5-nitro-2-(phenylthio)phenyl)-1,3,2-dioxaborolane (CAS 2377610-49-4)
- 4-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)phenyl)morpholine (CAS 906352-77-0)
- 4-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)phenyl)morpholine (CAS 651014-91-4)
Recommended Standards
- N-(3-Bromo-4-methylphenyl)-3-(trifluoromethyl)benzamide (CAS 876322-59-7)
- tert-Butyl 2-(iodomethyl)-1H-benzo[d]imidazole-1-carboxylate (CAS 1058225-52-7)
- N-(2-Bromophenyl)-N-methyl-3-(trifluoromethyl)benzamide (CAS 883106-32-9)
- tert-Butyl 5-iodo-3-methyl-1H-indazole-1-carboxylate (CAS 1180526-39-9)
- 6-Iodo-1,2,3,4-tetrahydroisoquinoline hydrochloride (CAS 1359701-92-0)
- 2-(2-Methoxyethyl)-1,5-dimethylpiperazine (CAS 1206679-48-2)
- 4-(tert-Butyl)-2-methylpyridine (CAS 97691-20-8)
- Pleuromutilin (CAS 125-65-5)
- N-{2-[(4-chlorophenyl)sulfanyl]-5-cyanophenyl}-3-(trifluoromethyl)benzamide (CAS 303147-33-3)
- n-(4-Methylphenyl)-2-(3-oxo-1,2,3,4-tetrahydroquinoxalin-2-yl)acetamide (CAS 36932-41-9)
- (S)-1-Boc-4,4-difluoro-2-(hydroxymethyl)pyrrolidine (CAS 215918-21-1)
- 2-Chloro-1-(4-cyclohexyl-piperazin-1-yl)-ethanonehydrochloride (CAS 1185296-59-6)
- N-ethyl-2-((2-methoxyethyl)amino)-N-phenylacetamide hydrochloride (CAS 1593109-76-2)
- Semaglutide impurity 244(Fmoc-His(Fmoc)-Aib-OH) (CAS CATO-C4X-2226244)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com