CDK 4/6 Inhibitor CAS 1256963-02-6
| CAS No. | 1256963-02-6 |
| Molecular Formula | C22H29ClN8 |
| Molecular Weight | 440.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), CDK 4/6 Inhibitor meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CDK 4/6 Inhibitor (CAS 1256963-02-6) is a high-purity analytical reference standard with the molecular formula C22H29ClN8 and a molecular weight of 440.97 g/mol.
CDK 4/6 Inhibitor (C22H29ClN8) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C22H29ClN8 |
| Molecular Weight | 440.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related CDK Standards
- BTk inhibitor 2 (CAS 1558036-85-3)
- CDK 1/2 Inhibitor III (CAS 443798-55-8)
- Cdk1/2 Inhibitor III (CAS 443798-47-8)
- 869304-55-2 Eg5 Inhibitor V, trans-24 DTXSID10468490 (CAS 869304-55-2)
- BTK inhibitor 8 (CAS 2230724-66-8)
- MMP3 inhibitor 2 (CAS 208663-26-7)
- PP1 inhibitor 1 (CAS 752216-12-9)
- GSK-3 Inhibitor X (CAS 740841-15-0)
Recommended Standards
- tert-butyl (4S)-4-(tert-butoxycarbonylamino)-3-chloro-2-methyl-spiro[4,6-dihydropyrrolo[1,2-b]pyrazole-5,4'-piperidine]-1'-carboxylate (CAS 2843691-06-3)
- (E)-3-((4-Chlorobenzyl)thio)-3-(phenylamino)-2-(phenylsulfonyl)acrylonitrile (CAS 866347-07-1)
- 2-(3-((4-Chlorophenyl)sulfonyl)propanamido)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 850023-30-2)
- N'-[(1E)-[4-(4-Chlorophenyl)-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5-trien-3-yl]methylidene]thiophene-2-carbohydrazide (CAS 866009-39-4)
- N-Methyl-1H-pyrazol-4-amine (CAS 28466-28-6)
- 5-Bromo-6-hydroxypyrimidine-4-carboxylic acid (CAS 135274-82-7)
- 3-(3-Methylisoxazol-5-yl)-2-(4-nitrophenyl)quinazolin-4(3H)-one (CAS 90059-42-0)
- 2-Fluoro-4-methyl-5-nitrobenzenesulfonyl chloride (CAS 1155084-24-4)
- Furan-3-carbohydrazide (CAS 70150-84-4)
- N-[4-(Acetylamino)phenyl]-2-(2-nitroethyl)benzenecarboxamide (CAS 339016-60-3)
- 1-[(3-Chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide (CAS 338977-69-8)
- 1-(6-Dimethylamino-pyridin-2-yl)ethanone (CAS 1060801-44-6)
- Methyl 2-amino-3-(oxolan-3-yl)propanoate (CAS 646055-78-9)
- Tirzepatide Impurity 43 (CAS CATO-C4X-324043)
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