2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid CAS 1257045-37-6
| CAS No. | 1257045-37-6 |
| Molecular Formula | C33H35ClN4O3 |
| Molecular Weight | 571.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid (CAS 1257045-37-6), molecular formula C33H35ClN4O3 and molecular weight 571.11 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid (C33H35ClN4O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C33H35ClN4O3 |
| Molecular Weight | 571.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related H Standards
- 2-(3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(1-(3-fluoro-2-(trifluoromethyl)isonicotinoyl)piperidin-4-yl)azetidin-3-yl)acetonitrile (CAS 1334298-90-6)
- 7H-Pyrrolo[2,3-d]pyrimidine-5-methanol, 4-chloro-7-[2-deoxy-3,5-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-beta-D-erythro-pentofuranosyl]- (CAS 1200462-11-8)
- 2H-pyrrolo[2,3-b]pyridin-2-one, 3,3,5-tribromo-1,3-dihydro-1-[[2-(trimethylsilyl)ethoxy]methyl]- (CAS 1229584-02-4)
- 1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid, 3-iodo-1-[(4-methylphenyl)sulfonyl]-, methyl ester (CAS 1198097-28-7)
- 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-iodo-1-[(4-methylphenyl)sulfonyl]- (CAS 348640-26-6)
- 1H-Pyrrolo[2,3-b]pyridine-2-carboxaldehyde, 1-(phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- (CAS 942920-60-7)
- 1H-Pyrrolo[2,3-b]pyridine, 3-iodo-1-[(4-methylphenyl)sulfonyl]- (CAS 664982-01-8)
- 173458-82-7 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-5,6-diphenyl-7-(phenylmethyl)- CTK0A7674 (CAS 173458-82-7)
Recommended Standards
- I-N-Octadecyl Disulfide (CAS 2500-88-1)
- Venetoclax Impurity 43 (CAS CATO-C4X-249543)
- 3,6-Di-tert-butyl 2-methyl 4-(benzyloxy)-8-(chloromethyl)-7,8-dihydropyrrolo[3,2-e]indole-2,3,6-tricarboxylate (CAS 539856-46-7)
- Venetoclax Impurity 9 (CAS 1235865-77-6)
- 2-(3-Bromophenyl)-6,8-dimethylquinoline-4-carbonyl chloride (CAS 1160262-79-2)
- 2-(4-(Methylsulfonyl)phenyl)imidazo[1,2-a]pyridine-6-carboxylic acid (CAS 866051-23-2)
- [3-(3-Fluorophenyl)-[1,2,4]triazolo[4,3-a]pyridin-6-yl]methanamine (CAS 1439902-26-7)
- 1-(4-(Trifluoromethoxy)phenethyl)piperazine dihydrochloride (CAS 958243-72-6)
- 5-Amino-1-methyl-1H-1,2,3-triazole-4-carboxamide (CAS 20419-66-3)
- 3-(4-Chlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione (CAS 125313-99-7)
- Tert-butyl 2,8-diazadispiro[3.1.3(6).1(4)]Decane-2-carboxylate (CAS 2168368-93-0)
- 2-(2-Ethoxypyridin-3-yl)piperidine-1-carbaldehyde (CAS 1352503-90-2)
- Methyl 3-vinylbenzoate (CAS 38383-50-5)
- Atrial Natriuretic Polypeptide (4-28), human (CAS 95896-08-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com