N-(4-Fluoro-3-nitrophenyl)-4-(trifluoromethyl)benzothioamide CAS 1257095-76-3
| CAS No. | 1257095-76-3 |
| Molecular Formula | C14H8F4N2O2S |
| Molecular Weight | 344.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-Fluoro-3-nitrophenyl)-4-(trifluoromethyl)benzothioamide.
CATO supplies N-(4-Fluoro-3-nitrophenyl)-4-(trifluoromethyl)benzothioamide (CAS 1257095-76-3), a certified reference material (molecular formula C14H8F4N2O2S, MW 344.28 g/mol) for analytical method development and quality control.
The molecular framework of N-(4-Fluoro-3-nitrophenyl)-4-(trifluoromethyl)benzothioamide (C14H8F4N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H8F4N2O2S |
| Molecular Weight | 344.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related N Standards
- 4-(2-fluoro-4-nitrophenoxy)-6,7-dimethoxyquinoline (CAS 516526-44-6)
- 4-(3-Fluoro-4-nitrophenoxy)-6,7-dimethoxyquinoline (CAS 228559-87-3)
- Methyl 1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)-5-methoxy-4-oxo-1,4-dihydropyridazine-3-carboxylate (CAS 1622861-41-9)
- Bis(4-fluoro-2-nitrophenyl) disulfide (CAS 796-69-0)
- {4-fluoro-1-[tris(propan-2-yl)silyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}boronic acid (CAS 2304634-59-9)
- (8-Fluoro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)(naphthalen-1-yl)methanone (CAS 254980-80-8)
- 7-Fluoro-2-[(4-methoxyphenyl)methylene]-3-phenyl-1-indanone (CAS 337921-27-4)
- [8-ethyl-7-fluoro-3-(methoxymethoxy)-1-naphthyl] 2,2-dimethylpropanoate (CAS 2621932-45-2)
Recommended Standards
- Theogallin (CAS 17365-11-6)
- N,N'-Bis(4-nitrophenyl)propanediamide (CAS 1900-40-9)
- Fingolimod Impurity 28 (CAS 162358-07-8)
- (4AR,6R,7aS)-2-hydroxy-6-(6-(methylthio)-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide (CAS 23526-12-7)
- 4-Amino-1-(perfluoroethyl)cyclohexan-1-ol hydrochloride (CAS 2770345-46-3)
- (3-Bromo-5-isopropoxyphenyl)methanol (CAS 1933562-20-9)
- methyl 2-(2,3-dichlorophenyl)-2-(methylamino)acetate hydrochloride (CAS 1989659-09-7)
- tert-Butyl (S)-2-(3-fluorophenyl)piperazine-1-carboxylate (CAS 1240588-45-7)
- Tert-butyl 4-(3-(2-fluorophenyl)ureido)piperidine-1-carboxylate (CAS 1233958-91-2)
- tert-Butyl (3-exo)-8-azabicyclo[3.2.1]octan-3-ylcarbamate hydrochloride (CAS 530135-00-3)
- 5-Amino-2-(4-nitrophenyl)pyrimidine (CAS 131548-43-1)
- 3-(m-Tolyl)-4-((4-(trifluoromethyl)benzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478256-32-5)
- N-(3-Chloro-4-methoxyphenyl)-2-((4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477329-99-0)
- Cholecystokinin Octapeptide (1-3) (desulfated) H-Asp-Tyr-Met-OH (CAS 121880-94-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com