4-(1,1-Difluoroethyl)piperidine CAS 1257379-92-2
| CAS No. | 1257379-92-2 |
| Molecular Formula | C7H13F2N |
| Molecular Weight | 149.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(1,1-Difluoroethyl)piperidine is closely related to fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(1,1-Difluoroethyl)piperidine (CAS 1257379-92-2), molecular formula C7H13F2N and molecular weight 149.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(1,1-Difluoroethyl)piperidine (C7H13F2N) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(1,1-Difluoroethyl)piperidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H13F2N |
| Molecular Weight | 149.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoroethyl Standards
- [1-(2,2-Difluoroethyl)cyclobutyl]methanamine (CAS 1849358-02-6)
- 4-(2,2-Difluoroethyl)piperidine (CAS 785756-04-9)
- 2,2-Difluoroethyl trifluoromethyl ether (CAS 84011-15-4)
- 1-(1,1-Difluoroethyl)cyclopropane-1-carboxylic acid (CAS 1447944-38-8)
- 1-(2,2-Difluoroethyl)cyclopropane-1-carboxylic acid (CAS 1541125-74-9)
- 2-(1,1-Difluoroethyl)cyclopropanecarboxylic acid (CAS 2229624-99-9)
- 2-(1,1-difluoroethyl)pyrazine (CAS 111781-49-8)
- 2-(1,1-difluoroethyl)piperazine (CAS 111781-50-1)
Recommended Standards
- 4,4-difluoro-3,3-dimethylpiperidine (CAS 1198392-56-1)
- (1R,4r)-4-(difluoromethyl)cyclohexan-1-amine (CAS 1267497-05-1)
- n-(Cyclobutylmethyl)-2,2-difluoroethan-1-amine (CAS 1178921-29-3)
- 4-(Difluoromethyl)cyclohexanamine (CAS 1314939-44-0)
- (S)-2,3-Dihydroxy-3-methylbutanoic acid (CAS 63903-90-2)
- 1-(2-(Ethylthio)ethyl)piperazine (CAS 702-07-8)
- 3,5-Difluoro-4-(thiomethyl)benzophenone (CAS 197439-19-3)
- Cy3.5 diacid(tetra so3) (CAS 769899-30-1)
- Dicyclohexylamine (S)-2-((tert-butoxycarbonyl)amino)-3-(3,4-dihydroxyphenyl)propanoate (CAS 102838-86-8)
- ethyl 13-(3-methyl-5-pentylfuran-2-yl)tridecanoate (CAS CATO-C4X-280623)
- Benzyl (2-(allylamino)ethyl)carbamate (CAS 112055-09-1)
- Butyl Mercaptoacetate (CAS 10047-28-6)
- 2-Acetoxy-2-methylbenzophenone (CAS 890098-87-0)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
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