methyl 5-fluoro-2,3-dihydroxy-benzoate CAS 1258002-30-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1258002-30-0
Molecular FormulaC8H7FO4
Molecular Weight186.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

methyl 5-fluoro-2,3-dihydroxy-benzoate CAS 1258002-30-0 chemical structure

Description

The occurrence of methyl 5-fluoro-2,3-dihydroxy-benzoate is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies methyl 5-fluoro-2,3-dihydroxy-benzoate (CAS 1258002-30-0), a certified reference material (molecular formula C8H7FO4, MW 186.14 g/mol) for analytical method development and quality control.

The molecular framework of methyl 5-fluoro-2,3-dihydroxy-benzoate (C8H7FO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), methyl 5-fluoro-2,3-dihydroxy-benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H7FO4
Molecular Weight186.14 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing

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