2,2-Difluoro-2-(4-hydroxypiperidin-4-yl)acetic acid hydrochloride CAS 1258638-18-4
| CAS No. | 1258638-18-4 |
| Molecular Formula | C7H11F2NO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2,2-Difluoro-2-(4-hydroxypiperidin-4-yl)acetic acid hydrochloride (CAS 1258638-18-4), molecular formula C7H11F2NO3HCl and molecular weight 231.62 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2,2-Difluoro-2-(4-hydroxypiperidin-4-yl)acetic acid hydrochloride is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 231.62 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H11F2NO3 HCl |
| Molecular Weight | 231.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 2-(4,5-Difluoro-2-nitrophenyl)acetic acid (CAS 1000339-22-9)
- 1-[6,8-Difluoro-2-(trifluoromethyl)quinol-4-yl]piperazine (CAS 1000339-47-8)
- 1-[6,8-Difluoro-2-(trifluoromethyl)quinol-4-yl]homopiperazine (CAS 1000339-49-0)
- 4,7-Difluoro-1H-indazole (CAS 1000341-68-3)
- 5,7-Difluoro-2H-indazole-3-carbaldehyde (CAS 1000343-25-8)
- 6,7-Difluoro-1H-indazol-3-ol (CAS 1000343-93-0)
- 2-(3,5-Difluoro-2-pyridyl)acetic acid (CAS 1000518-01-3)
- 2-(2,4-Difluoro-3-methylphenyl)acetic acid (CAS 1000545-11-8)
Recommended Standards
- 4-Bromobenzonitrile 13C (CAS 159528-78-6)
- 12-hydroxyjasmonic acid 12-O-beta-D-glucoside 120399-24-8 CHEBI:37419 Tuberonic acid glucoside {(1R,2R)-2-[(2Z)-5-(beta-D-glucopyranosyloxy)pent-2-en-1-yl]-3-oxocyclopentyl}acetic acid (CAS 120399-24-8)
- n-(4-Methylbenzyl)-6-oxo-1,6-dihydropyridazine-3-carboxamide (CAS 845983-71-3)
- 1-{2-amino-4H,5H,7H-thieno[2,3-c]pyran-3-yl}ethan-1-one (CAS 1467507-64-7)
- 2-(Oxazolidin-3-yl)ethanol (CAS 20073-50-1)
- 3-Isothiocyanatobenzamide (CAS 1224442-57-2)
- 2-Amino-6-methylpyrimidine-4(3H)-thione (CAS 6307-44-4)
- Sodium 2-chloro-1-hydroxyethane-1-sulfonate (CAS 13064-50-1)
- 6-Amino-4-chloropicolinic acid (CAS 1060808-93-6)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
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