4-(Chloromethyl)-2-(4-methanesulfonylphenyl)-1,3-thiazole CAS 1258641-29-0
| CAS No. | 1258641-29-0 |
| Molecular Formula | C11H10ClNO2S2 |
| Molecular Weight | 287.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-(Chloromethyl)-2-(4-methanesulfonylphenyl)-1,3-thiazole (CAS 1258641-29-0), a certified reference material (molecular formula C11H10ClNO2S2, MW 287.79 g/mol) for analytical method development and quality control.
The molecular framework of 4-(Chloromethyl)-2-(4-methanesulfonylphenyl)-1,3-thiazole (C11H10ClNO2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(Chloromethyl)-2-(4-methanesulfonylphenyl)-1,3-thiazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H10ClNO2S2 |
| Molecular Weight | 287.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Chloromethyl Standards
- 5-(Chloromethyl)-3-(3-phenoxypyridin-4-yl)-1,2,4-oxadiazole (CAS 1956307-09-7)
- 2-(3-(Chloromethyl)phenoxy)-5-(trifluoromethyl)pyridine (CAS 1020325-30-7)
- 5-(Chloromethyl)-2-(4-(trifluoromethoxy)phenyl)pyridine (CAS 851069-98-2)
- 5-(Chloromethyl)-n-(4-chlorophenyl)-1,3,4-thiadiazole-2-carboxamide (CAS 875159-92-5)
- 3-[5-(Chloromethyl)-1,2,4-oxadiazol-3-yl]-4-methoxybenzoyl chloride (CAS 1119449-67-0)
- 5-(Chloromethyl)isoxazol-3-yl (3-chlorophenyl)carbamate (CAS 866154-18-9)
- 6-(chloromethyl)-2-[4-(trifluoromethyl)phenyl]pyrimidin-4-ol (CAS 261959-08-4)
- 2-(Chloromethyl)-1,4-dihydroxyanthracene-9,10-dione (CAS 56594-53-7)
Recommended Standards
- 2-(4-Chlorophenoxy)-1-(2-thioxothiazolidin-3-yl)ethan-1-one (CAS 123529-83-9)
- 6-Benzyl-4-chloro-8,8-dimethyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS 1332455-40-9)
- 1-Benzyl-4-(6-chloropyridin-2-yl)piperazine (CAS 1220036-26-9)
- (5E)-5-[(5-Chloro-1,3-dimethyl-1H-pyrazol-4-yl)methylidene]-2-(methylsulfanyl)-4,5-dihydro-1,3-thiazol-4-one (CAS 956188-14-0)
- 2,2-Difluorooctahydro-3aH-indene-3a-carboxylic acid (CAS 1780300-27-7)
- 2-[1-(4-Chlorobenzenesulfonyl)piperidin-2-yl]ethan-1-amine (CAS 1828470-05-8)
- 1-(6-Chloropyridazin-3-yl)azetidin-3-ol (CAS 1020658-48-3)
- Itraconazole Impurity 21 (CAS CATO-C4X-149721)
- 4-Bromo-5-chloro-3-methyl-1-propyl-1H-pyrazole (CAS 29939-07-9)
- (R)-3,3'-Bis[4-(2-naphthalenyl)phenyl]-[1,1'-binaphthalene]-2,2'-diol (CAS 309934-86-9)
- 3-(Aminomethyl)-4-cyclopropoxy-N,N-dimethylaniline (CAS 1243472-55-0)
- (3-Amino-1-benzofuran-2-yl)(4-methylphenyl)methanone (CAS 333435-40-8)
- 3-((3-Methylcyclobutyl)methoxy)benzoic acid (CAS 1394021-04-5)
- Liraglutide Impurity 14 TFA Salt (CAS CATO-C4X-199214)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com