3,3-Bis(trifluoromethyl)cyclobutan-1-amine CAS 1258651-18-1
| CAS No. | 1258651-18-1 |
| Molecular Formula | C6H7F6N |
| Molecular Weight | 207.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3,3-Bis(trifluoromethyl)cyclobutan-1-amine.
3,3-Bis(trifluoromethyl)cyclobutan-1-amine (CAS 1258651-18-1), molecular formula C6H7F6N and molecular weight 207.12 g/mol, is a CATO reference standard with documented purity and traceability.
3,3-Bis(trifluoromethyl)cyclobutan-1-amine (C6H7F6N) contains fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7F6N |
| Molecular Weight | 207.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Bis Standards
- 3,4-Bis(trifluoromethyl)pyrrolidine (CAS 1355004-85-1)
- 3,4-bis(trifluoromethyl)-1H-pyrrole (CAS 82912-41-2)
- 4-Oxo-6-(trifluoromethyl)-4H-pyran-2-carboxamide (CAS 1029220-77-6)
- 6-Oxo-5-(trifluoromethyl)-1,6-dihydropyridine-3-carboxylic acid (CAS 1189757-60-5)
- 2-Oxo-6-(trifluoromethyl)-1,2-dihydropyridine-4-carboxylic acid (CAS 1227580-92-8)
- 6-Oxo-4-(trifluoromethyl)-1,6-dihydropyridine-2-carboxylic acid (CAS 1393558-71-8)
- 4-(Trifluoromethyl)nicotinic acid 1-oxide (CAS 178748-01-1)
- 2-Oxo-5-(trifluoromethyl)-1,2-dihydropyridine-3-carboxylic acid (CAS 787640-16-8)
Recommended Standards
- 2-(3,5-Dichlorophenyl)ethane-1-thiol (CAS 1174005-49-2)
- 2-(3,4-Dichlorophenyl)ethane-1-thiol (CAS 1267003-56-4)
- 2-Chloro-4-(chloromethyl)-1-(methylsulfanyl)benzene (CAS 109418-89-5)
- 1-(2,5-Dichlorophenyl)ethane-1-thiol (CAS 1039964-41-4)
- 6-Fluoro-1,4-dihydroquinoxaline-2,3-dione (CAS 61875-34-1)
- Methyl perfluorotridecanoate (CAS 185230-63-1)
- Methyl 2-(3-amino-4-bromophenyl)acetate (CAS 1261877-52-4)
- Dihydro-2H-thiopyran-3(4H)-one-1,1-dioxide (CAS 29431-37-6)
- CP 316 819 (CAS 186392-43-8)
- 86940-46-7 Praeroside II (CAS 86940-46-7)
- 7-Methyl-2,3-dihydrobenzofuran-3-amine (CAS 669-03-4)
- 4-Bromo-N-cyclohexylbenzenesulfonamide (CAS 7454-76-4)
- Methyl 2-(tetrahydrofuran-2-carboxamido)benzoate (CAS 495395-14-7)
- Semaglutide impurity 69 (CAS CATO-C4X-222669)
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