1-[2-(2-fluorophenyl)-2-oxoethyl]pyrrolidine-2,5-dione CAS 1258652-22-0
| CAS No. | 1258652-22-0 |
| Molecular Formula | C12H10FNO3 |
| Molecular Weight | 235.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-[2-(2-fluorophenyl)-2-oxoethyl]pyrrolidine-2,5-dione (C12H10FNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 1-[2-(2-fluorophenyl)-2-oxoethyl]pyrrolidine-2,5-dione (CAS 1258652-22-0), a certified reference material (molecular formula C12H10FNO3, MW 235.21 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-[2-(2-fluorophenyl)-2-oxoethyl]pyrrolidine-2,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10FNO3 |
| Molecular Weight | 235.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related fluorophenyl Standards
- 5-Ethyl-1-(4-fluorophenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1017470-82-4)
- 5-Ethyl-1-(3-fluorophenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1094311-25-7)
- Ethyl 5-(2-Fluorophenyl)isoxazole-3-carboxylate (CAS 1126636-56-3)
- Methyl 1-(2-fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate (CAS 1147207-80-4)
- 5-Ethyl-1-(2-fluorophenyl)-1h-1,2,4-triazole-3-carboxylic acid (CAS 1154370-83-8)
- [2-(4-Fluorophenyl)-4-methyl-1,3-oxazol-5-yl]acetic acid (CAS 1172370-81-8)
- Ethyl 5-(2-fluorophenyl)oxazole-4-carboxylate (CAS 127919-29-3)
- ethyl 5-(3-fluorophenyl)-1,3-oxaZole-4-carboxylate (CAS 127919-30-6)
Recommended Standards
- 1,6-dimethyl-4-(trifluoromethyl)-1H,2H,3H,4H,5H,6H,7H-pyrazolo[3,4-b]pyridin-3-one (CAS 1258641-11-0)
- Methyl 6-fluoro-4-methoxyquinoline-2-carboxylate (CAS 1260877-10-8)
- 1-(4-Fluoro-3-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid (CAS 1239728-42-7)
- 3-(6-Fluoro-4-oxoquinolin-1(4H)-yl)propanoic acid (CAS 1267499-14-8)
- 2-(4-Fluoro-3-methylphenyl)-3-methylbutan-2-ol (CAS 1338942-73-6)
- 2-(4-Amino-3-methylphenoxy)ethan-1-ol (CAS 103790-50-7)
- 3-(Tert-butyl) 9-methyl 3-azaspiro[5.5]Undecane-3,9-dicarboxylate (CAS 2005470-91-5)
- Saxagliptin Impurity 36 Mesylate (CAS 1564266-74-5)
- 1-(Pyrimidin-2-yl)pyrrolidin-3-amine dihydrochloride (CAS 2098048-53-2)
- [2,2'-Bipyridin]-5-ylmethanamine (CAS 220339-96-8)
- 2,3,4-Trifluoro-N-methylaniline (CAS 1021063-40-0)
- Tetraundecyl benzhydrol-3,3′,4,4′-tetracarboxylate (CAS 106327-92-8)
- 1,2-Dibromo-3,3,4,4,4-pentafluorobut-1-ene (CAS 1824865-30-6)
- D-Phe22-Tirzepatide (CAS CATO-CPTD788912)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com