5-Fluoro-2,4-dimethoxybenzene-1-sulfonyl chloride CAS 1258652-39-9
| CAS No. | 1258652-39-9 |
| Molecular Formula | C8H8ClFO4S |
| Molecular Weight | 254.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Fluoro-2,4-dimethoxybenzene-1-sulfonyl chloride (CAS 1258652-39-9) is a high-purity analytical reference standard with the molecular formula C8H8ClFO4S and a molecular weight of 254.66 g/mol.
The molecular framework of 5-Fluoro-2,4-dimethoxybenzene-1-sulfonyl chloride (C8H8ClFO4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8ClFO4S |
| Molecular Weight | 254.66 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Fluoro Standards
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Recommended Standards
- Dimorpholinophosphinyl Chloride (CAS 7264-90-6)
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- 3-((1,1,1-Trifluoropropan-2-yl)oxy)propane-1-sulfonyl chloride (CAS 1530785-87-5)
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- 2-Bromo-N-(naphthalen-1-yl)acetamide (CAS 1136-82-9)
- Methyl 6-methoxy-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate (CAS 40153-87-5)
- 1-Bromo-2-(bromomethyl)-4-methylbenzene (CAS 27561-50-8)
- Methyl 3-chloro-4-methyl-5-sulfamoylbenzoate (CAS 1340116-00-8)
- 2-((4-Fluoro-2-methylbenzyl)amino)propan-1-ol (CAS 1248387-92-9)
- 2-Chloro-3-((1-(methylsulfonyl)piperidin-3-yl)methyl)pyrazine (CAS 1316225-96-3)
- Benzyl (R)-2-(chloromethyl)pyrrolidine-1-carboxylate (CAS 1187932-05-3)
- D-Ser39-Tirzepatide (CAS CATO-CPTD788694)
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