8-(Trifluoromethyl)quinazolin-2-amine CAS 1258652-66-2
| CAS No. | 1258652-66-2 |
| Molecular Formula | C9H6F3N3 |
| Molecular Weight | 213.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 8-(Trifluoromethyl)quinazolin-2-amine (C9H6F3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 213.16 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 8-(Trifluoromethyl)quinazolin-2-amine (CAS 1258652-66-2), a certified reference material (molecular formula C9H6F3N3, MW 213.16 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H6F3N3 |
| Molecular Weight | 213.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 6-(Trifluoromethyl)quinazolin-4-amine (CAS 1020263-19-7)
- 3-(2-(Trifluoromethyl)phenyl)isoxazole (CAS 1093649-63-8)
- 5-(Trifluoromethyl)-1H-indole-7-carbaldehyde (CAS 1100215-34-6)
- 6-(Trifluoromethyl)-1H-indole-4-carbaldehyde (CAS 1100215-61-9)
- 4-(4-(Trifluoromethyl)phenyl)oxazole (CAS 1126636-40-5)
- 7-Trifluoromethyl-[1,8]naphthyridin-2-ylamine (CAS 1146081-30-2)
- 6-(Trifluoromethyl)isoquinolin-3-ol (CAS 1175271-49-4)
- 8-(Trifluoromethyl)isoquinolin-3-ol (CAS 1175271-71-2)
Recommended Standards
- 8-(Trifluoromethoxy)quinoline (CAS 1251032-62-8)
- 2-(4-Fluoro-5-methyl-2-nitrophenyl)acetic acid (CAS 1261079-63-3)
- 3-(Trifluoromethyl)quinolin-8-ol (CAS 124467-34-1)
- 3-(Trifluoromethyl)quinolin-7-ol (CAS 1261471-73-1)
- 2-(2,4-Dichlorophenoxy)-N-(4-(2-((2-methoxyethyl)amino)-2-oxoethyl)phenyl)acetamide (CAS 1060287-86-6)
- 3-Amino-N-(1,3-dimethyl-1H-pyrazol-5-yl)propanamide (CAS 1000381-70-3)
- 2-(3-Bromo-1H-1,2,4-triazol-1-yl)propanoic acid (CAS 1795275-25-0)
- (3-((Diethylcarbamoyl)oxy)pyridin-4-yl)boronic acid (CAS 868826-84-0)
- 3-(2-Methoxyphenyl)-N-(2-methylphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-62-0)
- 2-(Methylthio)-4-(trifluoromethyl)phenol (CAS 85092-99-5)
- Cyclopropyl methanesulfonate (CAS 1260105-11-0)
- lithium(1+) ion 5-benzyl-1,3-oxazole-2-carboxylate (CAS 1803585-61-6)
- Methyl 2-(4-bromophenyl)quinoline-4-carboxylate (CAS 350997-62-5)
- Semaglutide impurity 76 (CAS CATO-C4X-222676)
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