4,6-Dichloro-5-(2,4,5-trichlorophenyl)pyrimidin-2-amine CAS 1259478-93-7
| CAS No. | 1259478-93-7 |
| Molecular Formula | C10H4Cl5N3 |
| Molecular Weight | 343.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4,6-Dichloro-5-(2,4,5-trichlorophenyl)pyrimidin-2-amine (C10H4Cl5N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 4,6-Dichloro-5-(2,4,5-trichlorophenyl)pyrimidin-2-amine (CAS 1259478-93-7), a certified reference material (molecular formula C10H4Cl5N3, MW 343.42 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H4Cl5N3 |
| Molecular Weight | 343.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichloro Standards
- 4,5-Dichloro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 685513-95-5)
- 3,6-Dichloro-[1,2,4]triazolo[3,4-a]isoquinoline (CAS 7639-53-4)
- 2,4-Dichloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (CAS 950661-87-7)
- 3,4-Dichloro-α-[[[(3-methoxyphenyl)methyl]methylamino]methyl]-benzenemethanol-d3 (CAS 1794892-13-9)
- 2,5-Dichloro-N-(3-methylbenzo[d]thiazol-2(3H)-ylidene)thiophene-3-carboxamide (CAS 476626-89-8)
- 2-[2-(2,6-Dichloro-4-hydroxphenylamino)phenyl-d (CAS 1382084-40-3)
- Propyl 2,4-dichloro-6-(phenylthio)pyrimidine-5-carboxylate (CAS 87847-65-2)
- (E)-3-(2,3-Dichloro-4-((4-fluorophenyl)thio)phenyl)acrylicacid (CAS 929215-38-3)
Recommended Standards
- Diethyl 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)malonate (CAS 1257294-02-2)
- Papaverine Hydrochloride - Impurity E (CAS 13074-31-2)
- 1-(4-Fluorobenzyl)-3-((1-(methylsulfonyl)piperidin-4-yl)methyl)urea (CAS 1234972-02-1)
- JWH-073 Impurity 1 (JWH-073 5-Hydroxyindole Metabolite) (CAS 1307803-47-9)
- 2-((N-(2,4-dichloro-5-methoxyphenyl)-4-fluorophenyl)sulfonamido)-N,N-dimethylacetamide (CAS 338967-34-3)
- 2-Bromo-7-ethyl-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one (CAS 1208795-98-5)
- 3-(pyrrolidin-2-yl)-1,2,4-oxadiazole hydrochloride (CAS 1423033-80-0)
- Lasofoxifene Sulfate (CAS 1048953-96-3)
- 1-(3-Chlorophenyl)-5-phenyl-1H-pyrazole (CAS 299162-79-1)
- (R)-1-Methoxy-7,7-dimethyl-2-(prop-1-en-2-yl)-1,2,3,7-tetrahydroimidazo[1,2-a]pyrimidine (CAS 28340-21-8)
- (1R,3r,5S)-6,6-Difluorobicyclo[3.1.0]hexane-3-carbaldehyde (CAS 2126921-45-5)
- tert-Butyl 4-(4-aminophenyl)-5,6-dihydropyridine-1(2H)-carboxylate (CAS 873454-43-4)
- Trimethyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)silane (CAS 1186026-67-4)
- Semaglutide Main Chain P29 (CAS 1169630-82-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com