1-(8-Fluoro-2-methylquinolin-3-yl)ethanone CAS 1259519-87-3

Description

The occurrence of 1-(8-Fluoro-2-methylquinolin-3-yl)ethanone is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-(8-Fluoro-2-methylquinolin-3-yl)ethanone (CAS 1259519-87-3), molecular formula C12H10FNO and molecular weight 203.21 g/mol, is a CATO reference standard with documented purity and traceability.

1-(8-Fluoro-2-methylquinolin-3-yl)ethanone (C12H10FNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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