2-Bromo-1-[(4-methylbenzene)sulfonyl]-1H-indole CAS 1259576-89-0

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-1-[(4-methylbenzene)sulfonyl]-1H-indole.

2-Bromo-1-[(4-methylbenzene)sulfonyl]-1H-indole (CAS 1259576-89-0), molecular formula C15H12BrNO2S and molecular weight 350.23 g/mol, is a CATO reference standard with documented purity and traceability.

2-Bromo-1-[(4-methylbenzene)sulfonyl]-1H-indole (C15H12BrNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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