Fmoc-2-Amino-4,4-difluorobutyric acid CAS 1260640-43-4
| CAS No. | 1260640-43-4 |
| Molecular Formula | C19H17F2NO4 |
| Molecular Weight | 361.34 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Fmoc-2-Amino-4,4-difluorobutyric acid (CAS 1260640-43-4), molecular formula C19H17F2NO4 and molecular weight 361.34 g/mol, is a CATO reference standard with documented purity and traceability.
Fmoc-2-Amino-4,4-difluorobutyric acid (C19H17F2NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Fmoc-2-Amino-4,4-difluorobutyric acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H17F2NO4 |
| Molecular Weight | 361.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4,4-difluorobutanoic acid (CAS 1262802-55-0)
- Ethyl 2-(3-cyclopropyl-4-(difluoromethyl)-6-(furan-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1018050-88-8)
- 3-((2,4-Difluorophenoxy)methyl)-5-(4-ethoxy-3-methoxyphenyl)-1H-1,2,4-triazole (CAS 1416346-67-2)
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- (1-Iodoethyl)cyclopropane (CAS 86724-69-8)
- 5-(3-Fluorobenzyl)-2-morpholinothiazol-4-amine (CAS 1387566-15-5)
- CAS 64847-01-4 (CAS 64847-01-4)
- 7-Methoxy-2,4-dimethyl-1H-indole (CAS 190908-10-2)
- Tadalafil Impurity 171 (CAS CATO-C4X-1087171)
- 5-Acetyl-4-amino-2,6-dimethylpyridazin-3(2H)-one (CAS 175135-90-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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