2-Chloro-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine-4-carbaldehyde CAS 1260666-50-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1260666-50-9
Molecular FormulaC8H7ClN2O2
Molecular Weight198.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine-4-carbaldehyde CAS 1260666-50-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 198.61 g/mol gives 2-Chloro-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine-4-carbaldehyde distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Chloro-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine-4-carbaldehyde (CAS 1260666-50-9), molecular formula C8H7ClN2O2 and molecular weight 198.61 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Chloro-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine-4-carbaldehyde (C8H7ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Chloro-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine-4-carbaldehyde under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H7ClN2O2
Molecular Weight198.61 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentCl-containing
Nitrogen Atoms2

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