5-Chloro-2-iodo-3-methylpyrazine CAS 1260667-86-4
| CAS No. | 1260667-86-4 |
| Molecular Formula | C5H4ClIN2 |
| Molecular Weight | 254.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Chloro-2-iodo-3-methylpyrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Chloro-2-iodo-3-methylpyrazine (CAS 1260667-86-4) is a high-purity analytical reference standard with the molecular formula C5H4ClIN2 and a molecular weight of 254.46 g/mol.
The molecular framework of 5-Chloro-2-iodo-3-methylpyrazine (C5H4ClIN2) is characterized by a nitrile group, chlorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H4ClIN2 |
| Molecular Weight | 254.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-6-iodopyridin-3-amine (CAS 1032507-20-2)
- 5-Chloro-2-iodopyridin-3-amine (CAS 1057322-74-3)
- 4-Chloro-5-iodo-2-methylpyrimidine (CAS 111079-17-5)
- 6-Chloro-5-iodopyridin-2-amine, >97% (CAS 1221398-11-3)
- 5-Chloro-2-iodo-4-methylpyrimidine (CAS 1260810-52-3)
- 3-Chloro-5-iodopyridin-4-amine (CAS 1300750-79-1)
- 2-Chloro-4-iodopyridin-3-amine (CAS 153034-93-6)
- 5-Chloro-6-iodopyridin-3-amine (CAS 1628413-79-5)
Recommended Standards
- 2-Amino-5-chloro-4-iodopyridine (CAS 1260667-65-9)
- 2-Amino-6-chloro-4-iodopyridine (CAS 1062608-73-4)
- 4-Chloro-2-iodopyridin-3-amine (CAS 1805269-67-3)
- 5-Chloro-4-iodopyridin-3-amine (CAS 1807099-93-9)
- 2-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)thiazole-5-carbaldehyde (CAS 1890063-28-1)
- (11bS)-8,9,10,11,12,13,14,15-Octahydro-N,N-bis[(1R)-1-phenylethyl]-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-amine (CAS 479413-76-8)
- 3-(4-Chlorophenyl)-4-methyl-5-((1-phenylethyl)thio)-4H-1,2,4-triazole (CAS 792960-68-0)
- 3-Amino-5-fluoro-4-methylbenzamide (CAS 1118786-93-8)
- 1-Boc-3-(3'-chlorophenyl)-piperidin-4-one (CAS 869720-07-0)
- (4-Benzylpiperazin-1-yl)(piperidin-4-yl)methanone (CAS 188527-10-8)
- N-(3-chloro-4-methylphenyl)-2-(2-ethoxy-4-formylphenoxy)acetamide (CAS 579520-56-2)
- 2-{[(4-phenylphenyl)methyl]amino}acetamide (CAS 926266-27-5)
- 1,2-Ethanediamine, N2-(6-chloro-2-pyrazinyl)-N1,N1-dimethyl- 1219957-55-7 (CAS 1219957-55-7)
- Tau Peptide (306-336) (Repeat 3 Domain) trifluoroacetate salt (CAS 330456-26-3)
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