3-(2-Chloro-5-(trifluoromethoxy)phenyl)piperidine CAS 1260771-04-7
| CAS No. | 1260771-04-7 |
| Molecular Formula | C12H13ClF3NO |
| Molecular Weight | 279.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2-Chloro-5-(trifluoromethoxy)phenyl)piperidine (CAS 1260771-04-7), molecular formula C12H13ClF3NO and molecular weight 279.69 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(2-Chloro-5-(trifluoromethoxy)phenyl)piperidine (C12H13ClF3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(2-Chloro-5-(trifluoromethoxy)phenyl)piperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13ClF3NO |
| Molecular Weight | 279.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-2-(cyclohexyloxy)-5-(trifluoromethyl)pyridine (CAS 1216838-34-4)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)piperazine (CAS 1311279-54-5)
- 2-Chloro-N-ethyl-N-(3-(trifluoromethyl)benzyl)acetamide (CAS 1353982-20-3)
- n-[4-chloro-3-(trifluoromethyl)phenyl]-2,2-dimethylpropanamide (CAS 13691-92-4)
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- Methyl 4-hydroxy-4-(trifluoromethyl)cyclohexane-1-carboxylate (CAS 1782916-89-5)
- N-Phenyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-amine (CAS 124458-18-0)
- 4,4',4",4"'-(Pyrene-1,3,6,8-tetrayl)tetrakis(3-aminobenzoic acid) (CAS 2225892-57-7)
- Nsc118075 (CAS 120052-37-1)
- Testosterone EP Impurity J (CAS 57144-06-6)
- (E)-3-(2-(Methylthio)pyrimidin-5-yl)acrylic acid (CAS 915924-30-0)
- (3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(3-chlorophenyl)methanone (CAS 1823188-09-5)
- 2-(3,5-Bis(benzyloxy)phenyl)piperazine (CAS 65709-43-5)
- Naphthalen-2-ylmethyl ethanimidothioate hydrobromide (CAS 180002-24-8)
- Des-Gln19-Tirzepatide (CAS CATO-CPTD788954)
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