3-Bromo-1-(3-chloro-4-fluorobenzyl)pyrrolidin-2-one CAS 1260808-35-2
| CAS No. | 1260808-35-2 |
| Molecular Formula | C11H10BrClFNO |
| Molecular Weight | 306.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-Bromo-1-(3-chloro-4-fluorobenzyl)pyrrolidin-2-one (CAS 1260808-35-2), molecular formula C11H10BrClFNO and molecular weight 306.56 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Bromo-1-(3-chloro-4-fluorobenzyl)pyrrolidin-2-one (C11H10BrClFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10BrClFNO |
| Molecular Weight | 306.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
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