8-Fluoro-2-(trifluoromethyl)quinazoline CAS 1260822-46-5
| CAS No. | 1260822-46-5 |
| Molecular Formula | C9H4F4N2 |
| Molecular Weight | 216.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Fluoro-2-(trifluoromethyl)quinazoline (CAS 1260822-46-5), molecular formula C9H4F4N2 and molecular weight 216.14 g/mol, is a CATO reference standard with documented purity and traceability.
8-Fluoro-2-(trifluoromethyl)quinazoline (C9H4F4N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-Fluoro-2-(trifluoromethyl)quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H4F4N2 |
| Molecular Weight | 216.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- 2-Amino-1-(4,5-difluoro-2-nitrophenyl)ethan-1-one (CAS 1491068-11-1)
- 6-Amino-3-(methoxymethyl)benzo[d]oxazol-2(3h)-one (CAS 1478937-72-2)
- (R)-2-Amino-4-fluoro-4-methylpentanoic acid hydrochloride (CAS 1447616-15-0)
- 1-(2-(Cyclopentylamino)-2-oxoethyl)-1H-indole-4-carboxylic acid (CAS 1096815-42-7)
- Azetidine-3,3-dicarbonitrile (CAS 2168905-75-5)
- 1'-Isobutyl-2'-oxospiro[cyclopropane-1,3'-indoline]-2-carboxylic acid (CAS 2138280-52-9)
- 2-(4-methylphenyl)-pyrrolidine 2-(4-methylphenyl)pyrrolidine 2-p-Tolyl-pyrrolidine 62506-76-7 (CAS 62506-76-7)
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)-1H-pyrazole (CAS 1396750-11-0)
- (2S,4S)-1-(tert-butoxycarbonyl)-4-(3,4-dimethylphenoxy)pyrrolidine-2-carboxylic acid (CAS 1354486-23-9)
- 2-((2-Oxopyrazin-1(2H)-yl)oxy)acetic acid (CAS 761347-92-6)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
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