8-Iodo-3,4-dihydronaphthalen-2(1H)-one CAS 1260832-16-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1260832-16-3
Molecular FormulaC10H9IO
Molecular Weight272.08 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

8-Iodo-3,4-dihydronaphthalen-2(1H)-one CAS 1260832-16-3 chemical structure

Description

The occurrence of 8-Iodo-3,4-dihydronaphthalen-2(1H)-one is closely related to a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 8-Iodo-3,4-dihydronaphthalen-2(1H)-one (CAS 1260832-16-3), a certified reference material (molecular formula C10H9IO, MW 272.08 g/mol) for analytical method development and quality control.

The molecular framework of 8-Iodo-3,4-dihydronaphthalen-2(1H)-one (C10H9IO) is characterized by a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H9IO
Molecular Weight272.08 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentI-containing

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