3-Fluoro-5-(piperidin-3-yl)pyridine CAS 1260864-37-6
| CAS No. | 1260864-37-6 |
| Molecular Formula | C10H13FN2 |
| Molecular Weight | 180.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Fluoro-5-(piperidin-3-yl)pyridine.
3-Fluoro-5-(piperidin-3-yl)pyridine (CAS 1260864-37-6), molecular formula C10H13FN2 and molecular weight 180.22 g/mol, is a CATO reference standard with documented purity and traceability.
3-Fluoro-5-(piperidin-3-yl)pyridine (C10H13FN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Fluoro-5-(piperidin-3-yl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H13FN2 |
| Molecular Weight | 180.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 4-(4-Fluoro-3-methylphenyl)butan-2-one (CAS 1017209-93-6)
- 1-(4-Fluoro-3-methylphenyl)-2-methylpropan-1-one (CAS 1017211-24-3)
- 2-Fluoro-4-(piperidin-4-yl)pyridine (CAS 1138217-84-1)
- 5-Fluoro-2-(piperidin-4-yl)pyridine (CAS 1138217-86-3)
- 3-Fluoro-5-(piperidin-4-yl)pyridine (CAS 1138218-01-5)
- 1-(4-Fluoro-3-methylphenyl)butan-1-one (CAS 1175747-64-4)
- 1-(3-Fluoro-4-methylphenyl)butan-1-one (CAS 1178929-83-3)
- 2-Fluoro-6-(pyrrolidin-1-yl)aniline (CAS 1183840-96-1)
Recommended Standards
- 3-Fluoro-4-(piperidin-4-yl)pyridine (CAS 1260821-66-6)
- 5-fluoro-2-(piperidin-2-yl)pyridine (CAS 1270471-87-8)
- 3-Fluoro-4-(piperidin-3-yl)pyridine (CAS 1260645-80-4)
- 5-(Amino(cyclopropyl)methyl)-2-fluoroaniline (CAS 1270494-04-6)
- 4-(2-Hydroxyethyl)tetrahydro-2H-thiopyran 1,1-dioxide (CAS 1782025-98-2)
- Ethyl 5-amino-6-bromopicolinate (CAS 1805559-39-0)
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