[1-(6-Chloro-pyrimidin-4-yl)-piperidin-3-yl]-methyl-carbamic acid tert-butyl ester CAS 1261233-51-5
| CAS No. | 1261233-51-5 |
| Molecular Formula | C15H23ClN4O2 |
| Molecular Weight | 326.82 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of [1-(6-Chloro-pyrimidin-4-yl)-piperidin-3-yl]-methyl-carbamic acid tert-butyl ester is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies [1-(6-Chloro-pyrimidin-4-yl)-piperidin-3-yl]-methyl-carbamic acid tert-butyl ester (CAS 1261233-51-5), a certified reference material (molecular formula C15H23ClN4O2, MW 326.82 g/mol) for analytical method development and quality control.
The molecular framework of [1-(6-Chloro-pyrimidin-4-yl)-piperidin-3-yl]-methyl-carbamic acid tert-butyl ester (C15H23ClN4O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), [1-(6-Chloro-pyrimidin-4-yl)-piperidin-3-yl]-methyl-carbamic acid tert-butyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H23ClN4O2 |
| Molecular Weight | 326.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 3-(6-Chloro-2-methylsulfanyl-pyrimidin-4-yloxy)-piperidine-1-carboxylic acid tert-butyl ester (CAS 1261232-45-4)
- 3-Chloro-6-((S)-pyrrolidin-3-yloxy)-pyridazine hydrochloride (CAS 1261233-44-6)
- (2-Chloro-8-methyl-quinolin-3-ylmethyl)-(4-methoxy-benzyl)-amine (CAS 606095-52-7)
- 1-(2-Chloro-8-methylquinolin-3-yl)-N-(2-methoxybenzyl)methanamine (CAS 917746-08-8)
- 2-((E)-{3-[(2-Chloro-1,3-thiazol-5-yl)methoxy]phenyl}methylidene)-1-hydrazinecarbothioamide (CAS 477886-86-5)
- 3-Benzyl-7-chloro-2-isobutylquinazolin-4(3H)-one (CAS 587881-23-0)
- 5-Chloro-N-isobutyl-3-phenyl-2H-isoindole-1-carboxamide (CAS 61295-32-7)
- 6-Chloro-N-(4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-carbazol-1-amine (CAS 812649-16-4)
Recommended Standards
- tert-Butyl 4-(2-chloro-6-methylpyrimidin-4-yl)-2-methylpiperazine-1-carboxylate (CAS 1261233-45-7)
- Tert-butyl 4-[(2-chloropyrimidin-4-yl)(methyl)amino]piperidine-1-carboxylate (CAS 1261233-58-2)
- tert-Butyl 4-(4-chloro-5-methylpyrimidin-2-yl)-3-methylpiperazine-1-carboxylate (CAS 1261234-30-3)
- tert-Butyl 3-((6-chloropyridazin-3-yl)(methyl)amino)piperidine-1-carboxylate (CAS 1261233-41-3)
- (2,5-Dimethylphenyl)(pyridin-4-yl)methanone (CAS 776998-40-4)
- n-((1-Methyl-1h-pyrazol-4-yl)methyl)ethanamine hydrochloride (CAS 1209417-66-2)
- (3'-Fluoro[1,1'-biphenyl]-4-yl)acetonitrile (CAS 893734-08-2)
- 7-[1-(2-Fluorophenoxy)ethyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine (CAS 477865-09-1)
- 2,2,2-Trifluoro-1-(3-((trifluoromethyl)sulfonyl)phenyl)ethan-1-one (CAS 1335013-85-8)
- 1,1-bis(4-chlorophenyl)-2-{[(3-chlorophenyl)methyl]amino}ethan-1-ol 1J-327S 321432-85-3 (CAS 321432-85-3)
- Diethyl oxalimidate (CAS 13534-15-1)
- 4,4'-Dinonyl-2,2'-bithiazole (CAS 180729-91-3)
- 5-Amino-1-(3-ethoxyphenyl)-1H-pyrazole-4-carbonitrile (CAS 650629-04-2)
- [5-31]-Semaglutide (CAS CATO-C4X-2226263)
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