2-(2-(Difluoromethoxy)-5-nitrobenzoyl)pyridine CAS 1261531-87-6
| CAS No. | 1261531-87-6 |
| Molecular Formula | C13H8F2N2O4 |
| Molecular Weight | 294.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 294.21 g/mol gives 2-(2-(Difluoromethoxy)-5-nitrobenzoyl)pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(2-(Difluoromethoxy)-5-nitrobenzoyl)pyridine (CAS 1261531-87-6), molecular formula C13H8F2N2O4 and molecular weight 294.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2-(Difluoromethoxy)-5-nitrobenzoyl)pyridine (C13H8F2N2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2-(Difluoromethoxy)-5-nitrobenzoyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8F2N2O4 |
| Molecular Weight | 294.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethoxy Standards
- 2-(3-(Difluoromethoxy)-2-nitrobenzoyl)pyridine (CAS 1261587-39-6)
- 2-(4-(Difluoromethoxy)-2-nitrobenzoyl)pyridine (CAS 1261620-55-6)
- 2-(5-(Difluoromethoxy)-2-nitrobenzoyl)pyridine (CAS 1261678-39-0)
- (2-(Difluoromethoxy)-5-nitrophenyl)(pyridin-4-yl)methanone (CAS 1261807-65-1)
- 2-(3-(Difluoromethoxy)-4-nitrobenzoyl)pyridine (CAS 1261883-78-6)
- 3-{[2-(difluoromethoxy)phenyl]methoxy}benzoic acid (CAS 1095565-68-6)
- 2-(2-(Difluoromethoxy)-7-methylquinoxalin-5-yl)thiazole (CAS 2172977-15-8)
- 2-(Difluoromethoxy)-3,4,5,6-tetrafluorobenzenesulfonamide (CAS 2773501-56-5)
Recommended Standards
- 4-(benzylsulfanyl)-3-bromoaniline (CAS 1250718-37-6)
- 1-((3-Bromothiophen-2-yl)methyl)indoline (CAS 1223214-33-2)
- 2-(2-((1-(5-Bromothiophen-2-yl)ethyl)amino)ethoxy)ethan-1-ol (CAS 1179297-65-4)
- Favipiravir Impurity 21 (CAS CATO-C4X-210221)
- 2-Methoxy-3-methylquinoxaline (CAS 3149-26-6)
- 1-[4-(2-Chlorophenoxy)butyl]-1,4-diazepane (CAS 1240564-66-2)
- (1S,2S)-2-fluorocyclopropan-1-amine hydrochloride (CAS 1638744-20-3)
- 3-Bromo-4-(methylamino)benzamide (CAS 1369885-42-6)
- [1,2,5]Oxadiazolo[3,4-d]pyrimidine (CAS 14183-23-4)
- 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-((((hydroxymethyl)(methyl)amino)methyl)amino)pyrimidin-2(1H)-one (CAS 88699-77-8)
- H-Arg-Arg-βNA · 3 HCl (CAS 100900-26-3)
- 2-(1H-1,2,4-Triazol-5-yl)ethanamine dihydrochloride (CAS 7730-79-2)
- cis-4-[2-(3-Chlorophenyl)-2-oxoethyl]-cyclohexane-1-carboxylic acid (CAS 735275-58-8)
- Peptide 74 (H-8545.0500) (CAS 132116-39-3)
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