2-(4-(Difluoromethyl)-3-methylbenzoyl)pyridine CAS 1261533-27-0
| CAS No. | 1261533-27-0 |
| Molecular Formula | C14H11F2NO |
| Molecular Weight | 247.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(4-(Difluoromethyl)-3-methylbenzoyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-(4-(Difluoromethyl)-3-methylbenzoyl)pyridine (CAS 1261533-27-0), a certified reference material (molecular formula C14H11F2NO, MW 247.24 g/mol) for analytical method development and quality control.
2-(4-(Difluoromethyl)-3-methylbenzoyl)pyridine (C14H11F2NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H11F2NO |
| Molecular Weight | 247.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethyl Standards
- 2-(3-(Difluoromethyl)-4-methylbenzoyl)pyridine (CAS 1261468-47-6)
- 2-(2-(Difluoromethyl)-3-methylbenzoyl)pyridine (CAS 1261533-08-7)
- 2-(2-(Difluoromethyl)-6-methylbenzoyl)pyridine (CAS 1261671-97-9)
- (2-(Difluoromethyl)-5-methylphenyl)(pyridin-4-yl)methanone (CAS 1261729-60-5)
- 2-(2-(Difluoromethyl)-4-methylbenzoyl)pyridine (CAS 1261884-51-8)
- 2-((Difluoromethyl)thio)-N-methoxy-N-methylbenzamide (CAS 1274066-20-4)
- 2-((Difluoromethyl)sulfonyl)-1h-benzo[d]imidazol-6-amine (CAS 1249650-38-1)
- 2-(4-(Difluoromethyl)-2,6-dimethoxypyridin-3-yl)acetic acid (CAS 1804712-08-0)
Recommended Standards
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- ethyl 5,5-difluoro-4-oxo-6,7-dihydro-1H-indole-2-carboxylate (CAS 1263083-10-8)
- ((3-Fluorophenyl)sulfonyl)-L-alanine (CAS 1160933-45-8)
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- tert-Butyl 4-((4-(hydroxymethyl)benzyl)oxy)piperidine-1-carboxylate (CAS 937796-03-7)
- 4-Bromo-N-(2-(pyrrolidin-1-yl)ethyl)benzenesulfonamide (CAS 209968-27-4)
- H-Phe(3-Cl)-OH (CAS 80126-51-8)
- 3-(3-(Benzo[d][1,3]dioxol-5-yloxy)-2-oxopyrrolidin-1-yl)benzoic acid (CAS 649773-85-3)
- 1,4-Bis((4H-1,2,4-triazol-4-yl)methyl)benzene (CAS 1286189-21-6)
- 2-(2,4-Dichlorobenzoyl)-3-phenoxy-5-(trifluoromethyl)pyridine (CAS 306977-33-3)
- 5,6,7,8-Tetrahydropyrazolo[5,1-b][1,3]oxazepine-3-carboxylic acid (CAS 1545863-47-5)
- 4-Chloro-1-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 650628-68-5)
- (Des-Gly2)-Exenatide trifluoroacetate salt (CAS 1678416-78-8)
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