1-Bromo-2-(difluoromethyl)-3-methoxybenzene CAS 1261552-65-1
| CAS No. | 1261552-65-1 |
| Molecular Formula | C8H7BrF2O |
| Molecular Weight | 237.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Bromo-2-(difluoromethyl)-3-methoxybenzene.
1-Bromo-2-(difluoromethyl)-3-methoxybenzene (CAS 1261552-65-1) is a high-purity analytical reference standard with the molecular formula C8H7BrF2O and a molecular weight of 237.04 g/mol.
1-Bromo-2-(difluoromethyl)-3-methoxybenzene (C8H7BrF2O) contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Bromo-2-(difluoromethyl)-3-methoxybenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7BrF2O |
| Molecular Weight | 237.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-bromo-4-(difluoromethoxy)-2-methylbenzene (CAS 1021172-76-8)
- 6-Bromo-2,3-difluorophenetole (CAS 1122410-43-8)
- 5-Bromo-2-ethoxy-1,3-difluorobenzene (CAS 115467-04-4)
- 1-Bromo-2-(difluoromethyl)-4-methoxybenzene (CAS 1214329-81-3)
- 3-Bromo-4-(difluoromethyl)anisole (CAS 1214379-79-9)
- 4-Bromo-2,6-difluoro-alpha-methylbenzyl Alcohol (CAS 1214900-62-5)
- 1-Bromo-4-(difluoro(methoxy)methyl)benzene (CAS 1236031-38-1)
- 1-Bromo-2-ethoxy-3,5-difluorobenzene (CAS 1242418-44-5)
Recommended Standards
- 4-Bromo-2-(difluoromethyl)anisole (CAS 1261512-49-5)
- 2-Bromo-5-(difluoromethyl)anisole (CAS 1261569-65-6)
- 3-Bromo-5-(difluoromethyl)anisole (CAS 1261476-12-3)
- 2-Bromo-1-(difluoromethoxy)-3-methylbenzene (CAS 1261580-11-3)
- 4-[2-[4-[2-methoxy-5-[2-(1-methylquinolin-1-ium-4-yl)ethyl]phenoxy]phenyl]ethyl]-1-methyl-quinolin-1-ium diiodide (CAS 365542-47-8)
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- Semaglutide impurity 32 (CAS CATO-C4X-222632)
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