2-(2-Bromo-4-iodophenyl)-2-hydroxyacetic acid CAS 1261553-27-8
| CAS No. | 1261553-27-8 |
| Molecular Formula | C8H6BrIO3 |
| Molecular Weight | 356.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(2-Bromo-4-iodophenyl)-2-hydroxyacetic acid (CAS 1261553-27-8), molecular formula C8H6BrIO3 and molecular weight 356.94 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine/iodine substitution, an aromatic ring system, 2-(2-Bromo-4-iodophenyl)-2-hydroxyacetic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 356.94 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2-(2-Bromo-4-iodophenyl)-2-hydroxyacetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrIO3 |
| Molecular Weight | 356.94 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Br/I-containing |
Related Bromo Standards
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- methyl 5-bromo-2-hydroxy-3-iodobenZenecarboxylate (CAS 18071-51-7)
- 4-Bromo-5-iodo-1-(oxan-2-yl)pyrazole (CAS 1352318-61-6)
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- 3-Bromo-7-(2,4-dichlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidine (CAS 478249-01-3)
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Recommended Standards
- 5-Chloro-1-methyl-3-phenyl-4-({[4-(propan-2-yl)phenyl]sulfanyl}methyl)-1H-pyrazole (CAS 318234-19-4)
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- Anagrelide Impurity 14 (CAS CATO-C4X-224014)
- Mequitazine Impurity 2 (CAS 144827-81-6)
- 5-Methyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one (CAS 77712-95-9)
- 2-(Difluoromethyl)-5-hydroxy-3-nitropyridine-4-carbonyl chloride (CAS 1805540-19-5)
- (1-cyanocyclopropyl)methanesulfonamide (CAS 1461707-69-6)
- Ethyl 1-methyl-4-((4-methylbenzyl)amino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (CAS 1221715-29-2)
- L-741,626 (CAS 81226-60-0)
- ML115 (CAS 912798-42-6)
- 3-(4-bromophenyl)-4-(chloromethyl)-1-phenyl-1H-pyrazole (CAS 372107-20-5)
- (4-Bromo-2,3-dihydro-1H-inden-2-yl)methanol (CAS 1780552-74-0)
- 3-(3-(4-Chlorobenzyl)ureido)propanoic acid (CAS 1018300-38-3)
- Bax inhibitor peptide V5 (CAS 579492-81-2)
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