2-Chloro-4-(difluoromethoxy)-4'-(trifluoromethyl)-1,1'-biphenyl CAS 1261598-67-7
| CAS No. | 1261598-67-7 |
| Molecular Formula | C14H8ClF5O |
| Molecular Weight | 322.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-4-(difluoromethoxy)-4'-(trifluoromethyl)-1,1'-biphenyl (CAS 1261598-67-7), molecular formula C14H8ClF5O and molecular weight 322.66 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system, 2-Chloro-4-(difluoromethoxy)-4'-(trifluoromethyl)-1,1'-biphenyl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 322.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-4-(difluoromethoxy)-4'-(trifluoromethyl)-1,1'-biphenyl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8ClF5O |
| Molecular Weight | 322.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-3-(difluoromethoxy)-4'-(trifluoromethyl)-1,1'-biphenyl (CAS 1261669-54-8)
- 4-Chloro-7-ethoxy-6,8-dinitroquinoline-3-carbonitrile (CAS 1415564-65-6)
- Methyl 4-chloro-1-((5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)methyl)-1H-pyrazole-3-carboxylate (CAS 1006340-74-4)
- 3-Chloro-2-{[(2E)-2-(nitromethylidene)imidazolidin-1-yl]methyl}-5-(trifluoromethyl)pyridine (CAS 1354455-08-5)
- 5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-4,5-dihydro-1,2-oxazole-3-carboxamide (CAS 251310-33-5)
- 3-(4-Chloro-2-fluorophenyl)-1-methyl-6-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione (CAS 114136-66-2)
- 2-Chloro-4-fluoro-5-[1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]benzoic Acid (CAS 177489-17-7)
- 2-Chloro-N-(4-(cyanomethoxy)phenyl)-4,5-difluorobenzamide (CAS 1240841-59-1)
Recommended Standards
- 2-(3-(Trichlorosilyl)propyl)isoindoline-1,3-dione (CAS 62641-06-9)
- 4-(((5-Bromopyridin-2-yl)thio)methyl)-5-chloro-1,2,3-thiadiazole (CAS 1241418-85-8)
- 1,1,3,5,5-Pentamethyl-3-phenyl-1,5-divinyltrisiloxane (CAS 17902-95-3)
- 3,3'-(1,1,3,3,5,5-Hexamethyltrisiloxane-1,5-diyl)bis(propan-1-amine) (CAS 89467-59-4)
- 3-(tert-Butyl)-5,6-dihydro-4H-pyrrolo[3,2-d]isoxazole (CAS 603067-21-6)
- 2-(4-Chlorophenyl)-[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one (CAS 104614-80-4)
- (5S,6E,8Z)-5-Hydroxy-6,8-octadecadienoic Acid (CAS 1021188-23-7)
- Crisaborole lmpurity 82 (CAS CATO-C4X-202182)
- 3,3-Diphenylazetidine (CAS 7215-23-8)
- 3-(2-Methoxy-4-(trifluoromethoxy)phenyl)acrylic acid (CAS 1262019-21-5)
- DL-2-(Trifluoromethyl)-3-(3',4'-dihydroxy-phenyl)alanine (CAS 729-97-5)
- Metaraminol Bitartrate (CAS 33402-03-8)
- 3,4-Dichloro-N-(2-hydroxypropyl)benzenesulfonamide (CAS 1153554-99-4)
- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
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