2'-(Difluoromethoxy)-4'-(trifluoromethoxy)propiophenone CAS 1261616-31-2
| CAS No. | 1261616-31-2 |
| Molecular Formula | C11H9F5O3 |
| Molecular Weight | 284.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2'-(Difluoromethoxy)-4'-(trifluoromethoxy)propiophenone (CAS 1261616-31-2), a certified reference material (molecular formula C11H9F5O3, MW 284.18 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2'-(Difluoromethoxy)-4'-(trifluoromethoxy)propiophenone is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 2'-(Difluoromethoxy)-4'-(trifluoromethoxy)propiophenone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9F5O3 |
| Molecular Weight | 284.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Difluoromethoxy Standards
- 2'-(Difluoromethoxy)-3'-(trifluoromethoxy)propiophenone (CAS 1261568-25-5)
- 1-(4-(Difluoromethoxy)-2-(trifluoromethoxy)phenyl)propan-1-one (CAS 1261605-39-3)
- 3-(3-(2-(Difluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)propanoic acid (CAS 1708250-70-7)
- 3-(3-(3-(Difluoromethoxy)phenyl)-1,2,4-oxadiazol-5-yl)propanoic acid (CAS 1779133-19-5)
- 2-(4-(Difluoromethoxy)-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1310950-04-9)
- 2-(4-(Difluoromethoxy)-2-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246775-33-5)
- 5-{2-[4-(difluoromethoxy)phenyl]ethyl}-5-methylimidazolidine-2,4-dione (CAS 956684-89-2)
- 1-(Difluoromethoxy)-4-iodo-2-methylbenzene (CAS 1062613-63-1)
Recommended Standards
- (2-(5-Bromothiophen-2-yl)-6-methylpyrimidin-4-yl)methanamine (CAS 1339218-94-8)
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- 2-(4-Bromothiophen-2-yl)-5,6-dimethylpyrimidin-4-amine (CAS 1251313-29-7)
- 1-(2,5-Dimethoxyphenyl)-2,2,3,3,3-pentafluoropropan-1-one (CAS 1352207-90-9)
- N-(2-methoxyphenyl)-2-(propylamino)acetamide (CAS 731776-48-0)
- 5,8,10,14-Eicosatetraenoicacid, 12,20-dihydroxy-, (5Z,8Z,10E,12S,14Z)- 89614-44-8 ACMC-20locw (CAS 89614-44-8)
- Clenbuterol EP Impurity B (CAS 69708-36-7)
- 4-(2-Chlorophenyl)-2-fluorobenzoic acid (CAS 505082-99-5)
- 4-((9H-fluoren-9-ylidene)methyl)-N,N-dimethylaniline (CAS 2871-86-5)
- tert-Butyl (1-(2-chloronicotinoyl)piperidin-4-yl)(methyl)carbamate (CAS 1353973-16-6)
- N-(1-Cyanocyclopentyl)-2-((5-((4-ethylphenyl)amino)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 863420-46-6)
- 4-(3-Methoxy-4-methylphenyl)-2,2-dimethyl-4-oxobutanoic acid (CAS 951885-21-5)
- 4-((2-Aminoethyl)amino)benzenesulfonic acid (CAS 34898-77-6)
- Insulin Glargine (CAS 160337-95-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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