2-Bromo-4-(difluoromethoxy)-1-methoxybenzene CAS 1261775-66-9
| CAS No. | 1261775-66-9 |
| Molecular Formula | C8H7BrF2O2 |
| Molecular Weight | 253.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Bromo-4-(difluoromethoxy)-1-methoxybenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Bromo-4-(difluoromethoxy)-1-methoxybenzene (CAS 1261775-66-9) is a high-purity analytical reference standard with the molecular formula C8H7BrF2O2 and a molecular weight of 253.04 g/mol.
2-Bromo-4-(difluoromethoxy)-1-methoxybenzene (C8H7BrF2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H7BrF2O2 |
| Molecular Weight | 253.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4-Bromo-1-(difluoromethoxy)-2-methoxybenzene (CAS 1095544-42-5)
- 3-Bromo-5-(difluoromethoxy)anisole (CAS 1261446-31-4)
- 2-Bromo-1-(difluoromethoxy)-4-methoxybenzene (CAS 1261569-07-6)
- 1-Bromo-3-(difluoromethoxy)-2-methoxybenzene (CAS 1261644-78-3)
- 1-bromo-4-(difluoromethoxy)-2-methoxybenzene (CAS 1261679-30-4)
- 4-Bromo-2-(difluoromethoxy)-1-methoxybenzene (CAS 1261818-69-2)
- 1-Bromo-2,5-difluoro-4-(methoxymethoxy)benzene (CAS 1301145-79-8)
- (4-Bromo-3-difluoromethoxyphenyl)-methanol (CAS 1331943-89-5)
Recommended Standards
- [3-bromo-4-(difluoromethoxy)phenyl]methanol (CAS 1342005-84-8)
- 2,6-Dichloro-9-(2,2-difluoroethyl)-9H-purine (CAS 1199523-53-9)
- [2-bromo-5-(difluoromethoxy)phenyl]methanol (CAS 1427432-33-4)
- 2-(5-Amino-4-iodo-1H-pyrazol-1-yl)ethan-1-ol (CAS 1512571-32-2)
- 7-Trifluoromethyl-[1,8]naphthyridin-2-ylamine (CAS 1146081-30-2)
- 6-Chloro-7-nitro-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 116862-22-7)
- 6-Chloro-7-ethyl-2-methyl-7H-purine (CAS 1707571-15-0)
- 4,5-Diphenyl-4H-1,2,4-triazole-3-thiol (CAS 6596-82-3)
- 3-((tert-Butyldimethylsilyl)oxy)tetradecanal (CAS 213459-08-6)
- 5-Iodo-4-methylpyridin-2-ol (CAS 944718-23-4)
- 2-(Chloromethyl)-5-(2-chlorophenyl)-1,3,4-oxadiazole (CAS 24023-72-1)
- Ipragliflozin Impurity 11 (CAS CATO-C4X-188511)
- 4-Butyl-2-chloro-1-fluorobenzene (CAS 2432848-87-6)
- Semaglutide (CAS 910463-68-2（free base）)
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