2-(2-(Difluoromethoxy)-3-hydroxybenzoyl)pyridine CAS 1261787-16-9

Purity 97%+In StockPharmaceutical Standards
CAS No.1261787-16-9
Molecular FormulaC13H9F2NO3
Molecular Weight265.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(2-(Difluoromethoxy)-3-hydroxybenzoyl)pyridine CAS 1261787-16-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-(Difluoromethoxy)-3-hydroxybenzoyl)pyridine.

CATO supplies 2-(2-(Difluoromethoxy)-3-hydroxybenzoyl)pyridine (CAS 1261787-16-9), a certified reference material (molecular formula C13H9F2NO3, MW 265.21 g/mol) for analytical method development and quality control.

2-(2-(Difluoromethoxy)-3-hydroxybenzoyl)pyridine (C13H9F2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(2-(Difluoromethoxy)-3-hydroxybenzoyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H9F2NO3
Molecular Weight265.21 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms1

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