4-Chloro-2-(chloromethyl)-1-(trifluoromethoxy)benzene CAS 1261791-12-1
| CAS No. | 1261791-12-1 |
| Molecular Formula | C8H5Cl2F3O |
| Molecular Weight | 245.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 4-Chloro-2-(chloromethyl)-1-(trifluoromethoxy)benzene (C8H5Cl2F3O) contains a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 245.03 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-Chloro-2-(chloromethyl)-1-(trifluoromethoxy)benzene (CAS 1261791-12-1), molecular formula C8H5Cl2F3O and molecular weight 245.03 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-2-(chloromethyl)-1-(trifluoromethoxy)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl2F3O |
| Molecular Weight | 245.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-1-(chloromethyl)-4-(trifluoromethoxy)benzene (CAS 1261581-56-9)
- 2-Chloro-4-(chloromethyl)-1-(trifluoromethoxy)benzene (CAS 75462-57-6)
- 5-Chloro-4-(chlorosulfonyl)furan-2-carboxylic acid (CAS 2137610-41-2)
- 2-Chloro-N-(5-chlorobenzo[d]oxazol-2-yl)acetamide (CAS 64037-18-9)
- 6-Chloro-4-(chloromethyl)-7-hydroxy-2H-chromen-2-one (CAS 223420-30-2)
- 4-chloro-1-(methoxymethyl)-1H-pyrazole-5-sulfonyl chloride (CAS 1803611-49-5)
- 5-Chloro-2,2-dimethyl-2,3-dihydrobenzofuran-7-carbonyl chloride (CAS 189308-64-3)
- 2-[5-chloro-2-(chloromethyl)-1h-1,3-benzodiazol-1-yl]ethan-1-ol (CAS 1000932-85-3)
Recommended Standards
- 3-Bromo-4-nitrobenzamide (CAS 1261794-86-8)
- 2,5-Dichloro-alpha-(trifluoromethyl)benzyl Alcohol (CAS 1249336-72-8)
- 1,3-Dichloro-5-methyl-2-(trifluoromethoxy)benzene (CAS 1350760-79-0)
- 2-(4-bromo-2-hydroxyphenyl)-2-oxoacetic acid (CAS 1221724-46-4)
- 3-(trifluoromethyl)pyrrolidin-1-amine;hydrochloride (CAS 1432678-26-6)
- (+/-)-4-Methyl-2-azetidinone (CAS 5303-64-0)
- 4-Oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carbonitrile (CAS 1801143-20-3)
- 6-Bromo-3-methylimidazo[1,2-a]pyrimidine (CAS 1289193-67-4)
- Pentylsilane (CAS 10177-98-7)
- 2-(3-Nitrophenoxy)ethylamine (CAS 26646-35-5)
- tert-Butyl (4aR,7aR)-hexahydropyrrolo[3,4-b][1,4]oxazine-4(4aH)-carboxylate (CAS 1932337-68-2)
- (S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethan-1-amine hydrochloride (CAS 1646543-17-0)
- Edaravone impurity 53 (CAS 92558-29-7)
- Endo-Gly29-Tirzepatide (CAS CATO-CPTD788685)
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