5-(Difluoromethoxy)-2,3'-bis(trifluoromethyl)-1,1'-biphenyl CAS 1261822-85-8

Description

Compared with other compounds in its class, the molecular weight of 356.21 g/mol gives 5-(Difluoromethoxy)-2,3'-bis(trifluoromethyl)-1,1'-biphenyl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-(Difluoromethoxy)-2,3'-bis(trifluoromethyl)-1,1'-biphenyl (CAS 1261822-85-8) is a high-purity analytical reference standard with the molecular formula C15H8F8O and a molecular weight of 356.21 g/mol.

Owing to a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, 5-(Difluoromethoxy)-2,3'-bis(trifluoromethyl)-1,1'-biphenyl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 356.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(Difluoromethoxy)-2,3'-bis(trifluoromethyl)-1,1'-biphenyl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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