5-(2-(Trifluoromethoxy)phenyl)-1-indanone CAS 1261833-75-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1261833-75-3
Molecular FormulaC16H11F3O2
Molecular Weight292.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-(2-(Trifluoromethoxy)phenyl)-1-indanone CAS 1261833-75-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 292.25 g/mol gives 5-(2-(Trifluoromethoxy)phenyl)-1-indanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-(2-(Trifluoromethoxy)phenyl)-1-indanone (CAS 1261833-75-3) is a high-purity analytical reference standard with the molecular formula C16H11F3O2 and a molecular weight of 292.25 g/mol.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, 5-(2-(Trifluoromethoxy)phenyl)-1-indanone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 292.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H11F3O2
Molecular Weight292.25 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing

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