(2-(Difluoromethyl)-6-nitrophenyl)(pyridin-4-yl)methanone CAS 1261884-76-7
| CAS No. | 1261884-76-7 |
| Molecular Formula | C13H8F2N2O3 |
| Molecular Weight | 278.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies (2-(Difluoromethyl)-6-nitrophenyl)(pyridin-4-yl)methanone (CAS 1261884-76-7), a certified reference material (molecular formula C13H8F2N2O3, MW 278.21 g/mol) for analytical method development and quality control.
Structurally, (2-(Difluoromethyl)-6-nitrophenyl)(pyridin-4-yl)methanone (C13H8F2N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 278.21 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H8F2N2O3 |
| Molecular Weight | 278.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoromethyl Standards
- 5-(Difluoromethyl)-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 101527-46-2)
- (4-(Difluoromethyl)-2-nitrophenyl)(pyridin-4-yl)methanone (CAS 1261592-99-7)
- 2-(2-(Difluoromethyl)-4-nitrobenzoyl)pyridine (CAS 1261621-45-7)
- 2-(3-(Difluoromethyl)-4-nitrobenzoyl)pyridine (CAS 1261672-32-5)
- (2-(Difluoromethyl)-3-nitrophenyl)(pyridin-4-yl)methanone (CAS 1261799-81-8)
- 2-(2-(Difluoromethyl)-3-nitrobenzoyl)pyridine (CAS 1261843-49-5)
- 2-(2-(Difluoromethyl)-5-nitrobenzoyl)pyridine (CAS 1261884-63-2)
- Ethyl 4-(difluoromethyl)-2-phenylpyrimidine-5-carboxylate (CAS 1708437-52-8)
Recommended Standards
- 3,3'-Difluoro-[1,1'-biphenyl]-4,4'-dicarboxylic acid (CAS 1261929-07-0)
- 5-(4-Carboxy-3-fluorophenyl)-2-fluorobenzoic acid (CAS 1261956-34-6)
- 4-(3-Carboxy-5-fluorophenyl)-2-fluorobenzoic acid (CAS 1261978-52-2)
- 3-(4-Carboxy-3-fluorophenyl)-4-fluorobenzoic acid (CAS 1262001-65-9)
- N-(3,4-Difluorobenzyl)-5-(quinolin-8-yl)pyridin-3-amine (CAS 920529-87-9)
- Z-Val-Lys-Lys-Arg-4MbNA hydrochloride salt (CAS 71003-01-5)
- 2-((Methylsulfonyl)methyl)nicotinic acid (CAS 1691896-14-6)
- 4-Fluoro-3-(trifluoromethyl)phenylhydrazine Hydrochloride (CAS 502496-22-2)
- 3-Hydroxy-3-(4-(trifluoromethoxy)phenyl)propanenitrile (CAS 1520504-56-6)
- 11-Bromotetraphene (CAS 1263386-46-4)
- 123501-43-9 4,6-DIAMINOPYRIMIDINE SULFATE DTXSID60482782 (CAS 123501-43-9)
- 1-(Aminocarbonyl)piperidine-3-carboxylic acid (CAS 871478-82-9)
- Lopinavir Impurity 26 (CAS CATO-C4X-168226)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
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