[3-(Trifluoromethyl)[1,1-biphenyl]-2-yl]-methanamine CAS 1261888-24-7

Description

The occurrence of [3-(Trifluoromethyl)[1,1-biphenyl]-2-yl]-methanamine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

[3-(Trifluoromethyl)[1,1-biphenyl]-2-yl]-methanamine (CAS 1261888-24-7) is a high-purity analytical reference standard with the molecular formula C15H14F3N and a molecular weight of 265.27 g/mol.

The molecular framework of [3-(Trifluoromethyl)[1,1-biphenyl]-2-yl]-methanamine (C15H14F3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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