3-(Furan-2-yl)-5-(trifluoromethyl)benzoic acid CAS 1261952-66-2
| CAS No. | 1261952-66-2 |
| Molecular Formula | C12H7F3O3 |
| Molecular Weight | 256.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 256.18 g/mol gives 3-(Furan-2-yl)-5-(trifluoromethyl)benzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-(Furan-2-yl)-5-(trifluoromethyl)benzoic acid (CAS 1261952-66-2), a certified reference material (molecular formula C12H7F3O3, MW 256.18 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H7F3O3, 3-(Furan-2-yl)-5-(trifluoromethyl)benzoic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 256.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H7F3O3 |
| Molecular Weight | 256.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
Related Furan Standards
- 2-(Furan-2-ylmethylene)-3-oxo-2,3-dihydrobenzofuran-5-carboxylic acid (CAS 71620-29-6)
- 2-(Furan-3-yl)-4-oxo-4H-chromene-3-carboxylic acid (CAS 89002-87-9)
- (E)-2-(furan-2-ylmethylene)-4-methyl-3-oxo-4-(1H-1,2,4-triazol-1-yl)pentanenitrile (CAS 338759-07-2)
- 3-(Furan-2-ylmethyl)-1-methylquinazoline-2,4(1H,3H)-dione (CAS 531504-02-6)
- 5-(Furan-2-carbonyl)-1,3,4,5-tetrahydro-2H-benzo[b][1,4]diazepin-2-one (CAS 866134-28-3)
- N-(Furan-2-ylmethyl)-5-methylfuro[3,2-b]pyridine-2-carboxamide (CAS 941881-14-7)
- {1-[(Furan-2-yl)methyl]-2-methanesulfonyl-1h-imidazol-5-yl}methanol (CAS 1221342-05-7)
- 2-(4-(3-(Furan-2-yl)-1H-pyrazol-5-yl)piperidin-1-yl)acetonitrile (CAS 321848-25-3)
Recommended Standards
- 1-(2-(Trifluoromethyl)phenyl)-1H-pyrazole-4-carboxylic acid (CAS 1260855-51-3)
- (S)-1-(3-bromo-5-methylphenyl)pentan-1-amine (CAS 1269790-41-1)
- 1-[4-(Trifluoromethyl)phenyl]pyrazole-4-carboxylic Acid (CAS 1260740-53-1)
- (R)-1-(3-bromo-5-methylphenyl)pentan-1-amine (CAS 1269980-75-7)
- 5-Bromo-3-iodo-2-methyl-2H-indazole (CAS 865156-35-0)
- 6-Isopropyl-4-methyl-2-oxo-2H-chromene-3-carbonitrile (CAS 288399-89-3)
- Didanosine - Impurity I (CAS 7057-48-9)
- 2-(2-((3-Chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)amino)ethoxy)ethyl 4-chlorobenzoate (CAS 331462-33-0)
- 1-methyl-1H,4H,5H,6H,7H-pyrrolo[2,3-c]pyridine hydrochloride (CAS 1394040-48-2)
- N,N-dimethyl-3-(3-(pyrazin-2-yl)propyl)azetidine-3-carboxamide (CAS 1361112-34-6)
- (4-Methylpyridin-3-yl)(3-(trifluoromethyl)phenyl)methanone (CAS 1187168-61-1)
- Fmoc-α-Me-Glu(OtBu)-OH (CAS 1072845-48-7)
- (2R,3R,4R,5R,6R)-5-acetamido-2-(acetoxymethyl)-6-bromotetrahydro-2H-pyran-3,4-diyl diacetate (CAS 39541-21-4)
- D-Ala35-Tirzepatide (CAS CATO-CPTD788904)
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