2-Chloro-4-(3,4-difluorophenyl)benzoic acid CAS 1261956-79-9
| CAS No. | 1261956-79-9 |
| Molecular Formula | C13H7ClF2O2 |
| Molecular Weight | 268.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 2-Chloro-4-(3,4-difluorophenyl)benzoic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 268.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Chloro-4-(3,4-difluorophenyl)benzoic acid (CAS 1261956-79-9), molecular formula C13H7ClF2O2 and molecular weight 268.64 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H7ClF2O2 |
| Molecular Weight | 268.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-5-(3,4-difluorophenyl)benzoic acid (CAS 1179627-16-7)
- 4-(3-Chloro-4-fluorophenyl)-3-fluorobenzoic acid (CAS 1261922-99-9)
- 4-(3-Chloro-5-fluorophenyl)-3-fluorobenzoic acid (CAS 1261970-29-9)
- 2-Chloro-4-(2,6-difluorophenyl)benzoic acid (CAS 1262006-10-9)
- 7-CHLORO-6-(TRIFLUOROMETHYL)BENZO[B]THIOPHENE 1,1-DIOXIDE (CAS 1446401-38-2)
- 3-Chloro-2',4'-difluoro-[1,1'-biphenyl]-4-carboxylic acid (CAS 505082-89-3)
- (E)-3-(3-Chloro-2-fluoro-6-(1H-tetrazol-1-yl)phenyl)acrylic acid (CAS 1094106-58-7)
- 1-(4-Chloro-3-nitrobenzyl)pyrrolidine-2,5-dione (CAS 1097788-45-8)
Recommended Standards
- 4-Cyano-5-(difluoromethoxy)pyridine-3-sulfonyl chloride (CAS 924886-42-0)
- 4-Chloro-1-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazine-3-carboxylic acid (CAS 339096-24-1)
- Ethyl 4,4,4-trifluoro-3-sulfobutanoate (CAS 1803598-32-4)
- 1-(chloromethyl)-3,5-bis(trifluoromethyl)benzene (CAS 75462-59-8)
- Methyl 3-(4-bromo-1h-pyrazol-1-yl)-2-(propylamino)propanoate (CAS 1248490-82-5)
- 4-(4,5-Diphenyl-1H-imidazol-2-yl)benzonitrile (CAS 29898-72-4)
- Imidazo[1,2-b]pyridazine-6-carboxylic acid hydrochloride (CAS 316352-05-3)
- 2-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)benzoic acid (CAS 56813-55-9)
- Methyl (3S,4S)-4-(difluoromethyl)pyrrolidine-3-carboxylate (CAS 1807936-86-2)
- tert-Butyl ((2S)-2-(hydroxymethyl)-4-oxoazetidin-3-yl)carbamate (CAS 2166342-77-2)
- (S)-di-tert-butyl 2-cyanopiperazine-1,4-dicarboxylate (CAS 1242267-80-6)
- 4-(Tetrahydrofuran-2-yl)tetrahydro-2H-pyran-4-amine (CAS 2137450-80-5)
- Aminooxy-PEG8-acid (CAS 2055269-60-6)
- Cholecystokinin Octapeptide (desulfated) (H-2070.0005) (CAS 198483-36-2)
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