5-Hydroxy-4'-methyl-[1,1'-biphenyl]-3-carboxylic acid CAS 1261978-76-0
| CAS No. | 1261978-76-0 |
| Molecular Formula | C14H12O3 |
| Molecular Weight | 228.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Hydroxy-4'-methyl-[1,1'-biphenyl]-3-carboxylic acid (C14H12O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
5-Hydroxy-4'-methyl-[1,1'-biphenyl]-3-carboxylic acid (CAS 1261978-76-0) is a high-purity analytical reference standard with the molecular formula C14H12O3 and a molecular weight of 228.24 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Hydroxy-4'-methyl-[1,1'-biphenyl]-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12O3 |
| Molecular Weight | 228.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
Related Hydroxy Standards
- 3-Hydroxy-4'-methoxy-[1,1'-biphenyl]-4-carbaldehyde (CAS 1014625-93-4)
- 2-Hydroxy-5-methylphenyl benzoate (CAS 10268-64-1)
- 4-Hydroxy-4'-(hydroxymethyl)-[1,1'-biphenyl]-3-carbaldehyde (CAS 1098984-09-8)
- 2'-Hydroxy-2-methyl-[1,1'-biphenyl]-4-carboxylic acid (CAS 1141473-81-5)
- Methyl 3-hydroxy-[1,1'-biphenyl]-4-carboxylate (CAS 117369-94-5)
- 2-(4'-Hydroxy-[1,1'-biphenyl]-2-yl)acetic acid (CAS 1176610-22-2)
- Ethyl 8-hydroxy-1,4-dioxaspiro[4.5]Dec-7-ene-7-carboxylate (CAS 121210-56-8)
- 4'-Hydroxy-2-methyl-[1,1'-biphenyl]-3-carboxylic acid (CAS 1261993-26-3)
Recommended Standards
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- Semaglutide impound 212 (CAS CATO-C4X-2226212)
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