2-Hydroxy-5-(thiophen-3-yl)pyridine-3-carboxylic acid CAS 1262004-20-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1262004-20-5
Molecular FormulaC10H7NO3S
Molecular Weight221.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Hydroxy-5-(thiophen-3-yl)pyridine-3-carboxylic acid CAS 1262004-20-5 chemical structure

Description

2-Hydroxy-5-(thiophen-3-yl)pyridine-3-carboxylic acid (CAS 1262004-20-5), molecular formula C10H7NO3S and molecular weight 221.23 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 2-Hydroxy-5-(thiophen-3-yl)pyridine-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 221.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Hydroxy-5-(thiophen-3-yl)pyridine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H7NO3S
Molecular Weight221.23 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Nitrogen Atoms1
Sulfur Atoms1

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