5-(4-Chlorophenyl)-6-hydroxynicotinic acid CAS 1262010-75-2
| CAS No. | 1262010-75-2 |
| Molecular Formula | C12H8ClNO3 |
| Molecular Weight | 249.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(4-Chlorophenyl)-6-hydroxynicotinic acid.
5-(4-Chlorophenyl)-6-hydroxynicotinic acid (CAS 1262010-75-2) is a high-purity analytical reference standard with the molecular formula C12H8ClNO3 and a molecular weight of 249.65 g/mol.
The molecular framework of 5-(4-Chlorophenyl)-6-hydroxynicotinic acid (C12H8ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(4-Chlorophenyl)-6-hydroxynicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8ClNO3 |
| Molecular Weight | 249.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- 5-(4-Chlorophenyl)-2-hydroxyisonicotinic acid (CAS 1261954-43-1)
- 1-(2-Chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1267134-04-2)
- 1-(4-Chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1267681-65-1)
- 1-(3-Chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1268028-62-1)
- 1-(3-chlorophenyl)-6-oxo-1,6-dihydropyridine-3-carboxylic acid (CAS 1284635-72-8)
- 5-(3-Chlorophenyl)-3-hydroxypicolinic acid (CAS 1415226-40-2)
- 6-(3-chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 147269-19-0)
- 6-(2-Chlorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 147283-47-4)
Recommended Standards
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- 6-Chloro-4-methyl-5-nitro-3,3'-bipyridine (CAS 1214390-89-2)
- 3-(6-Chloro-2H-chromen-3-yl)-1,2,4-oxadiazol-5-amine (CAS 1269532-10-6)
- 4-Phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride (CAS 208108-75-2)
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- (4-(Methoxymethoxy)-2,3-dihydrobenzofuran-6-yl)methanol (CAS 1219924-29-4)
- 2-(3-Bromo-4-fluorophenyl)-4-(trifluoromethyl)-1H-imidazole (CAS 1309602-29-6)
- 4-(5-Butyl-1,2,4-oxadiazol-3-yl)aniline (CAS 10364-73-5)
- Lithium tungsten oxide, 99% min (CAS 13568-45-1)
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- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
Why CATO?
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