Fosfomycin Trometamol EP Impurity B CAS 1262243-11-7
| CAS No. | 1262243-11-7 |
| Molecular Formula | C7H18NO7P |
| Molecular Weight | 259.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Fosfomycin Trometamol EP Impurity B (C7H18NO7P) is characterized by a carbohydrate-derived structure, an amide group, a phosphate ester group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Fosfomycin Trometamol EP Impurity B (CAS 1262243-11-7, C7H18NO7P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H18NO7P |
| Molecular Weight | 259.19 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | -0.5 |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
Related Fosfomycin Standards
- Fosfomycin Impurity 80 (CAS CATO-C4X-131680)
- Fosfomycin Impurity 69 (CAS CATO-C4X-131669)
- Fosfomycin Impurity 65 (CAS 15205-62-6)
- Fosfomycin Impurity 24 (CAS 1416734-33-2)
- Fosfomycin Impurity 79 (CAS CATO-C4X-131679)
- Fosfomycin Impurity 67 (CAS CATO-C4X-131667)
- Fosfomycin Impurity 38 (CAS 25383-05-5)
- Fosfomycin Impurity 60 (CAS 135578-84-6)
Recommended Standards
- 3,5-Bis(trifluoromethyl)phenylacetonitrile 3,5-bis(trifluoromethyl)-phenylacetonitrile 3,5-di(trifluoro methyl)benzyl cyanide 3,5-bis(trifluoromethyl)benzylcyanide 3,5-bis(trifluoromethyl)benzyl cyanide 85068-32-2 (CAS 85068-32-2)
- 9-bromopyrazolo[5,1-a]isoquinoline (CAS 2766427-63-6)
- n-((1-(Difluoromethyl)-1h-imidazol-2-yl)methyl)-3,5-difluoroaniline (CAS 1094402-15-9)
- 8-bromopyrazolo[5,1-a]isoquinoline (CAS 2766427-60-3)
- Bedaquiline Impurity 17 (CAS CATO-C4X-116717)
- Lacosamide Impurity 17 (CAS CATO-C4X-183017)
- Zopiclone impurity 28 (CAS 69433-07-4)
- Ethyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride (CAS 57980-74-2)
- 2-(2-((Benzyl(methyl)amino)methyl)piperidin-1-yl)acetic acid (CAS 1353948-30-7)
- 2-Bromohexanoylbromide (CAS 54971-26-5)
- 5-Chloro-1-(2-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 1152971-26-0)
- Tert-butyl (((2R,4R)-4-hydroxypyrrolidin-2-yl)methyl)carbamate (CAS 1314605-34-9)
- 3-Cyclopropyl-1-ethyl-1H-pyrazole-4-carbaldehyde (CAS 1006490-05-6)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
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