tert-Butyl 3-fluoro-3-(hydroxymethyl)pyrrolidine-1-carboxylate CAS 1262410-84-3
| CAS No. | 1262410-84-3 |
| Molecular Formula | C10H18FNO3 |
| Molecular Weight | 219.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies tert-Butyl 3-fluoro-3-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 1262410-84-3), a certified reference material (molecular formula C10H18FNO3, MW 219.25 g/mol) for analytical method development and quality control.
The molecular framework of tert-Butyl 3-fluoro-3-(hydroxymethyl)pyrrolidine-1-carboxylate (C10H18FNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H18FNO3 |
| Molecular Weight | 219.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 4-Fluoro-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester (CAS 1260772-97-1)
- tert-Butyl (2R,3S)-3-fluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 1272599-12-8)
- N-(2-fluoro-5-methylbenzyl)-1-(furan-2-yl)methanamine (CAS 1249727-53-4)
- tert-Butyl (3R,4R)-4-fluoro-3-hydroxypiperidine-1-carboxylate (CAS 1314641-02-5)
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- Peptide Impurity (CAS CATO-CPTD788810)
Why CATO?
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