Tert-butyl 4,4-difluoro-2,8-diazaspiro[4.5]Decane-8-carboxylate CAS 1263178-02-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1263178-02-4
Molecular FormulaC13H22F2N2O2
Molecular Weight276.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Tert-butyl 4,4-difluoro-2,8-diazaspiro[4.5]Decane-8-carboxylate CAS 1263178-02-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 276.32 g/mol gives Tert-butyl 4,4-difluoro-2,8-diazaspiro[4.5]Decane-8-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Tert-butyl 4,4-difluoro-2,8-diazaspiro[4.5]Decane-8-carboxylate (CAS 1263178-02-4) is a high-purity analytical reference standard with the molecular formula C13H22F2N2O2 and a molecular weight of 276.32 g/mol.

The molecular framework of Tert-butyl 4,4-difluoro-2,8-diazaspiro[4.5]Decane-8-carboxylate (C13H22F2N2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H22F2N2O2
Molecular Weight276.32 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2

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