3-Iodo-6-methoxy-1H-indole-2-carboxylic acid CAS 1263206-35-4
| CAS No. | 1263206-35-4 |
| Molecular Formula | C10H8INO3 |
| Molecular Weight | 317.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Iodo-6-methoxy-1H-indole-2-carboxylic acid.
3-Iodo-6-methoxy-1H-indole-2-carboxylic acid (CAS 1263206-35-4) is a high-purity analytical reference standard with the molecular formula C10H8INO3 and a molecular weight of 317.08 g/mol.
The molecular framework of 3-Iodo-6-methoxy-1H-indole-2-carboxylic acid (C10H8INO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Iodo-6-methoxy-1H-indole-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8INO3 |
| Molecular Weight | 317.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
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- 2-Iodo-8-methoxyindolizine-7-carboxylic acid (CAS 1706460-08-3)
- Ethyl 3-iodo-1H-pyrazolo[3,4-c]pyridine-5-carboxylate (CAS 2089326-71-4)
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Recommended Standards
- 2-(2-Iodoethoxy)isoindoline-1,3-dione (CAS 1100696-50-1)
- Ethyl 6-iodobenzo[d]isoxazole-3-carboxylate (CAS 1352395-67-5)
- Ethyl 6-iodoimidazo[1,2-b]pyridazine-2-carboxylate (CAS 1005786-10-6)
- 5-((2,2-Difluoroethoxy)methyl)-4-iodo-1-methyl-1H-pyrazol-3-amine (CAS 1354705-87-5)
- Indanidine (CAS 85392-79-6)
- 2-(2-Fluorophenyl)-2-oxoacetaldehyde hydrate (CAS 170880-96-3)
- (R)-3-Methyl-6-(prop-1-en-2-yl)cyclohex-2-enone (CAS 80995-97-7)
- methyl 4-(diphenylphosphoryl)benzoate (CAS 5032-55-3)
- 1-(4-Methyl-2-(thiophen-3-yl)thiazol-5-yl)ethan-1-one (CAS 56421-74-0)
- 10Alpha-hydroxy-exo-THC (CAS 56986-42-6)
- 2-(2,3,5,6-Tetrafluoro-4-methylphenyl)-N-(3-(trifluoromethyl)phenyl)hydrazine-1-carboxamide (CAS 1022566-18-2)
- Benzyl 3-amino-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate (CAS 1416373-96-0)
- 2-(Cyclobutylamino)cyclohexan-1-ol (CAS 1247916-90-0)
- Semaglutide impurity 261 (CAS CATO-C4X-2226261)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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