3-Chloroisoquinoline-7-carboxylic acid CAS 1263207-80-2
| CAS No. | 1263207-80-2 |
| Molecular Formula | C10H6ClNO2 |
| Molecular Weight | 207.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-Chloroisoquinoline-7-carboxylic acid (CAS 1263207-80-2), a certified reference material (molecular formula C10H6ClNO2, MW 207.61 g/mol) for analytical method development and quality control.
The molecular framework of 3-Chloroisoquinoline-7-carboxylic acid (C10H6ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3-Chloroisoquinoline-7-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H6ClNO2 |
| Molecular Weight | 207.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloroisoquinoline Standards
- 1-Chloroisoquinoline-3-carboxylic acid (CAS 1049606-80-5)
- 3-Chloroisoquinoline-1-carboxylic acid (CAS 1179149-10-0)
- 6-Chloroisoquinoline-1-carboxylic acid (CAS 1179149-30-4)
- 4-Chloroisoquinoline-1-carboxylic acid (CAS 1179149-31-5)
- 5-Chloroisoquinoline-1-carboxylic acid (CAS 1179149-33-7)
- 3-Chloroisoquinoline-4-carboxylic acid (CAS 123695-38-5)
- 1-Chloroisoquinoline-6-carboxylic acid (CAS 1256787-42-4)
- 3-Chloroisoquinoline-6-carboxylic acid (CAS 1256794-71-4)
Recommended Standards
- 3-(4-Chloro-3-cyanophenyl)acrylic acid (CAS 1262012-18-9)
- 7-Chloroquinoline-4-carboxylic Acid (CAS 13337-66-1)
- 7-Hydroxyquinoline-3-carbonyl chloride (CAS 1261845-43-5)
- 3-Chloroisoquinoline-8-carboxylic acid (CAS 1337880-43-9)
- Maltosine (CAS 121502-04-3)
- (2-(3-Chlorophenoxy)phenyl)methanamine (CAS 186700-05-0)
- 5-Amino-1-methyl-1H-benzo[d]imidazole-2-carboxylic acid (CAS 1369157-13-0)
- 4-(2,2-Difluorocyclopropyl)piperidine hydrochloride (CAS 2097991-05-2)
- 1-(3-Fluorophenethyl)piperazine (CAS 188400-93-3)
- N-(3-(2-(benzyloxy)ethoxy)propyl)thietan-3-amine (CAS 1994092-16-8)
- 2-Chloro-5-((4-methoxyphenoxy)methyl)thiazole (CAS 339018-20-1)
- Ethyl 5-bromo-2-cyanothiophene-3-carboxylate (CAS 2090354-40-6)
- 4-Chloro-3-nitro-1H-pyrrolo[2,3-b]pyridine (CAS 918519-53-6)
- Prolactin-Releasing Peptide (1-31) (rat) (CAS 215510-06-8)
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